ReviewRNA biology2014
mRNA localization in the Drosophila germline.
Review in RNA biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- The cytoskeleton regulates cytoophidium dynamics in Drosophila ovaries.Cell & bioscience · 2026Article
- smFISH: Quantifying and Mapping RNA at the Single-Molecule Level.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Whole transcriptome screening for novel genes involved in meiosis and fertility in Drosophila melanogaster.Scientific reports · 2024Article
- Article
- dTtc1, a conserved tetratricopeptide repeat protein, is required for maturation ofFrontiers in cell and developmental biology · 2023Article
- Transcriptome-scale methods for uncovering subcellular RNA localization mechanisms.Biochimica et biophysica acta. Molecular cell research · 2022Review
- Dynein light chain-dependent dimerization of Egalitarian is essential for maintaining oocyte fate in Drosophila.Developmental biology · 2021Article
- mRNA Targeting, Transport and Local Translation in Eukaryotic Cells: From the Classical View to a Diversity of New Concepts.Molecular biology · 2021Article
- Granule regulation by phase separation during Drosophila oogenesis.Emerging topics in life sciences · 2020Review
- mRNA Localization in Plant Cells.Plant physiology · 2020Review
- Organizing the oocyte: RNA localization meets phase separation.Current topics in developmental biology · 2020Article
- Review
- The cytoplasmic dynein transport machinery and its many cargoes.Nature reviews. Molecular cell biology · 2018Review
- Review
- The mRNA transportome of the BicD/Egl transport machinery.RNA biology · 2017Article
- Translational control of gurken mRNA in Drosophila development.Cell cycle (Georgetown, Tex.) · 2017Article
- Poly(ADP-Ribosyl)ation of hnRNP A1 Protein Controls Translational Repression in Drosophila.Molecular and cellular biology · 2016Article
- Article
- Localized Translation of gurken/TGF-α mRNA during Axis Specification Is Controlled by Access to Orb/CPEB on Processing Bodies.Cell reports · 2016Article
- Diverse and pervasive subcellular distributions for both coding and long noncoding RNAs.Genes & development · 2016Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Localization and the associated translational control of mRNA is a well established mechanism for segregating cellular protein expression. Drosophila has been instrumental in deciphering the prevailing mechanisms of mRNA localization and regulation. This review will discuss the diverse roles of mRNA localization in the Drosophila germline, the cis-elements and cellular components regulating localization and the superimposition of translational regulatory mechanisms. Despite a history of discovery, there are still many fundamental questions regarding mRNA localization that remain unanswered. Take home messages, outstanding questions and future approaches that will likely lead to resolving these unknowns in the future are summarized at the end.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.