ReviewRNA biology2014
Of social molecules: The interactive assembly of ASH1 mRNA-transport complexes in yeast.
Review in RNA biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- The RNA structural code: orchestrating gene expression and enabling precision therapies.Acta pharmacologica Sinica · 2026Review
- Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth.Nature communications · 2025Article
- EDNRA affects susceptibility to large artery atherosclerosis stroke through potential inflammatory pathway.Scientific reports · 2024Article
- Tunable cell differentiation via reprogrammed mating-type switching.Nature communications · 2024Article
- Post-transcriptional control of fungal cell wall synthesis.Cell surface (Amsterdam, Netherlands) · 2022Article
- DeeReCT-APA: Prediction of Alternative Polyadenylation Site Usage Through Deep Learning.Genomics, proteomics & bioinformatics · 2022Article
- Alternative polyadenylation of mRNA and its role in cancer.Genes & diseases · 2021Review
- RNA-biology ruling cancer progression? Focus on 3'UTRs and splicing.Cancer metastasis reviews · 2020Review
- Pan-tissue analysis of allelic alternative polyadenylation suggests widespread functional regulation.Molecular systems biology · 2020Article
- mRNA Localization in Plant Cells.Plant physiology · 2020Review
- Probing the RNA-Binding Proteome from Yeast to Man: Major Advances and Challenges.Methods in molecular biology (Clifton, N.J.) · 2019Article
- mRNA localization in metazoans: A structural perspective.RNA biology · 2017Review
- Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.Nature structural & molecular biology · 2017Article
- An RNA-binding atypical tropomyosin recruits kinesin-1 dynamically to oskar mRNPs.The EMBO journal · 2017Article
- Global analysis of regulatory divergence in the evolution of mouse alternative polyadenylation.Molecular systems biology · 2016Article
- A new isoform of Drosophila non-muscle Tropomyosin 1 interacts with Kinesin-1 and functions in oskar mRNA localization.Journal of cell science · 2016Article
- Evolution and Biological Roles of Alternative 3'UTRs.Trends in cell biology · 2016Review
- How Dynein Moves Along Microtubules.Trends in biochemical sciences · 2016Review
- ASH1 mRNP-core factors form stable complexes in absence of cargo RNA at physiological conditions.RNA biology · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asymmetric, motor-protein dependent transport of mRNAs and subsequent localized translation is an important mechanism of gene regulation. Due to the high complexity of such motile particles, our mechanistic understanding of mRNA localization is limited. Over the last two decades, ASH1 mRNA localization in budding yeast has served as comparably simple and accessible model system. Recent advances have helped to draw an increasingly clear picture on the molecular mechanisms governing ASH1 mRNA localization from its co-transcriptional birth to its delivery at the site of destination. These new insights help to better understand the requirement of initial nuclear mRNPs, the molecular basis of specific mRNA-cargo recognition via cis-acting RNA elements, the different stages of RNP biogenesis and reorganization, as well as activation of the motile activity upon cargo binding. We discuss these aspects in context of published findings from other model organisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.