ReviewNucleus (Austin, Tex.)
Polymer models of interphase chromosomes.
Review in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Tuning nuclear rheology through transient chromatin cross-links.Physical review. E · 2025Article
- Closing the loops: chromatin loop dynamics after DNA damage.Nucleus (Austin, Tex.) · 2025Review
- Different relative scalings between transient forces and thermal fluctuations tune regimes of dynamic clustering.Physical review. E · 2025Article
- The power of weak, transient interactions across biology: A paradigm of emergent behavior.Physica D. Nonlinear phenomena · 2023Article
- Review
- Shaping centromeres to resist mitotic spindle forces.Journal of cell science · 2022Article
- Review
- Simulating Dynamic Chromosome Compaction: Methods for Bridging In Silico to In Vivo.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Nonequilibrium Biophysical Processes Influence the Large-Scale Architecture of the Cell Nucleus.Biophysical journal · 2020Article
- Transient crosslinking kinetics optimize gene cluster interactions.PLoS computational biology · 2019Article
- Statistics of chromatin organization during cell differentiation revealed by heterogeneous cross-linked polymers.Nature communications · 2019Article
- Keep moving and stay in a good shape to find your homologous recombination partner.Current genetics · 2019Review
- Enrichment of dynamic chromosomal crosslinks drive phase separation of the nucleolus.Nucleic acids research · 2017Article
- Chromatin stiffening underlies enhanced locus mobility after DNA damage in budding yeast.The EMBO journal · 2017Article
- Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage.Molecular biology of the cell · 2017Article
- Microtubule dynamics drive enhanced chromatin motion and mobilize telomeres in response to DNA damage.Molecular biology of the cell · 2017Article
- Systems-level chromosomal parameters represent a suprachromosomal basis for the non-random chromosomal arrangement in human interphase nuclei.Scientific reports · 2016Article
- Entropy gives rise to topologically associating domains.Nucleic acids research · 2016Article
- Mechanobiology of Chromatin and the Nuclear Interior.Cellular and molecular bioengineering · 2016Article
- DNA loops generate intracentromere tension in mitosis.The Journal of cell biology · 2015Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Clear organizational patterns on the genome have emerged from the statistics of population studies of fixed cells. However, how these results translate into the dynamics of individual living cells remains unexplored. We use statistical mechanics models derived from polymer physics to inquire into the effects that chromosome properties and dynamics have in the temporal and spatial behavior of the genome. Overall, changes in the properties of individual chains affect the behavior of all other chains in the domain. We explore two modifications of chain behavior: single chain motion and chain-chain interactions. We show that there is not a direct relation between these effects, as increase in motion, doesn't necessarily translate into an increase on chain interaction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.