Evidence map›Paper›PMID 25482181›Full record

ReviewNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2015

Regulation of extrasynaptic glutamate levels as a pathophysiological mechanism in disorders of motivation and addiction.

Robert E McCullumsmith, Gerard Sanacora

Open access · bronzeAbstract readReview
In one paragraph

Review in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Effectiveness of N-acetylcysteine in Treating Clinical Symptoms of Substance Abuse and Dependence: A Meta-analysis of Randomized Controlled Trials.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Riluzole Impairs Cocaine Reinstatement and Restores Adaptations in Intrinsic Excitability and GLT-1 Expression.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Article
  15. Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Robert E McCullumsmithDepartment of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Gerard SanacoraClinical Neuroscience Research Unit, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
University of Cincinnati Medical Center · USYale University · US

Funding

Effects of Stress and Glutamatergic Agents on Glutamate Cycling and BehaviorR01MH081211 · NIMH · YALE UNIVERSITY · PI SANACORA, GERARD · 2009 to 2013
$1.8M
Defects of subcellular glutamate transporter localization in schizophreniaR01MH094445 · NIMH · UNIVERSITY OF CINCINNATI · PI MCCULLUMSMITH, ROBERT E · 2011 to 2015
$1.7M
Abnormalities of glutamate transporter localization in schizophreniaR21MH087752 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCCULLUMSMITH, ROBERT E, ROBERTS, ROSALINDA C · 2011 to 2012
$403k
NIMH NIH HHS MH081211NIMH NIH HHS MH087752NIMH NIH HHS MH094445NIMH NIH HHS R01 MH081211NIMH NIH HHS R01 MH094445
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBehavior, AddictiveGlutamic AcidHumansMotivationSodium-Glucose Transport ProteinsSynapsesGlutamic AcidSodium-Glucose Transport Proteins

Identifiers

PMID25482181
PMCPMC4262905
OpenAlexW1973712162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.