ArticleInternational journal of cardiology2015
Infective endocarditis in the Lao PDR: clinical characteristics and outcomes in a developing country.
Article in International journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Perception Regarding the NICE Guideline on Antibiotic Prophylaxis against Infective Endocarditis Following Dental Procedures: A Cross-Sectional Study.Antibiotics (Basel, Switzerland) · 2023Article
- Infective endocarditis in developing countries: An update.Frontiers in cardiovascular medicine · 2022Review
- Clinical Characteristics and Risk Factors for in-Hospital Mortality in 240 Cases of Infective Endocarditis in a Tertiary Hospital in China: A Retrospective Study.Infection and drug resistance · 2022Article
- Infective endocarditis at a tertiary-care hospital in China.Journal of cardiothoracic surgery · 2020Article
- Factors Affecting Mortality in Patients with Blood-Culture Negative Infective Endocarditis.The International journal of angiology : official publication of the International College of Angiology, Inc · 2020Article
- A changing profile of infective endocarditis at a tertiary hospital in China: a retrospective study from 2001 to 2018.BMC infectious diseases · 2019Article
- Infective endocarditis: innovations in the management of an old disease.Nature reviews. Cardiology · 2019Review
- Early results for active infective endocarditis.The Pan African medical journal · 2017Article
- Article
- Diagnosis of blood culture-negative endocarditis and clinical comparison between blood culture-negative and blood culture-positive cases.Infection · 2016Article
- Article
- Newly diagnosed rheumatic heart disease among indigenous populations in the Pacific.Heart (British Cardiac Society) · 2015Article
- Bartonella henselae endocarditis in Laos - 'the unsought will go undetected'.PLoS neglected tropical diseases · 2014Article
- Clinical - microbiological characterization and risk factors of mortality in infective endocarditis from a tertiary care academic hospital in Southern India.Indian heart journalArticle
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
Abstract
introductionData on infective endocarditis (IE) in Southeast Asia are scarce.
objectivesTo describe the clinical epidemiology of IE in Lao PDR, a lower middle-income country.
methodsA single centre retrospective study at Mahosot Hospital, Vientiane. Patients aged over 1year of age admitted 2006-2012 to Mahosot Hospital with definite or possible IE by modified Duke criteria were included.
resultsThirty-six patients fulfilled the inclusion criteria; 33 (91.7%) had left-sided IE. Eleven (30.6%) had definite IE and 25 (69.4%) possible left-sided IE. Median age was 25years old [IQR 18-42]. Fifteen patients (41.7%) were males. Underlying heart diseases included: rheumatic valve disease in 12 (33.3%), congenital heart disease in 7 (19.4%), degenerative valve disease in 3 (8.3%), and of unknown origin in 14 (38.9%) patients. Native valve IE was present in 30 patients (83.3%), and prosthetic valve IE in 6 patients (16.7%). The most frequent pathogens were Streptococcus spp. in 7 (19.4%). Blood cultures were negative in 22 patients (61.1%). Complications included: heart failure in 11 (30.6%), severe valve regurgitation in 7 (19.4%); neurological event in 7 (19.4%); septic shock or severe sepsis in 5 (13.9%); and cardiogenic shock in 3 patients (8.3%). No patient underwent heart surgery. Fourteen (38.9%) had died by follow-up after a median of 2.1years [IQR 1-3.2]; and 3 (8.3%) were lost to follow-up.
conclusionsInfective endocarditis, a disease especially of young adults and mainly caused by Streptococcus spp., was associated with rheumatic heart disease and had high mortality in Laos.
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