Trial reportJournal of the National Cancer Institute2014
Increasing colon cancer screening in primary care among African Americans.
Trial report in Journal of the National Cancer Institute, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 6 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Pooled it
- Components and effectiveness of patient navigation programmes to increase participation to breast, cervical and colorectal cancer screening: A systematic review.Cancer medicine · 2023Pooled it
- Systematic Review of Interventions to Increase Stool Blood Colorectal Cancer Screening in African Americans.Journal of community health · 2021Pooled it
- Interventions for increasing colorectal cancer screening uptake among African-American men: A systematic review and meta-analysis.PloS one · 2020Pooled it
- The Case for Patient Navigation in Lung Cancer Screening in Vulnerable Populations: A Systematic Review.Population health management · 2019Pooled it
- Pooled it
- Homelessness, Patient Navigation, and Lung Cancer Screening in a Health Center Setting: A Subgroup Analysis of a Randomized Clinical Trial.JAMA network open · 2025Trial
- Process Evaluation of a Mailed Interactive Educational DVD in a Comparative Effectiveness Trial to Promote Colorectal Cancer Screening.Health promotion practice · 2022Trial
- Precision Patient Navigation to Improve Rates of Follow-up Colonoscopy, An Individual Randomized Effectiveness Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2021Trial
- Computer-tailored intervention increases colorectal cancer screening among low-income African Americans in primary care: Results of a randomized trial.Preventive medicine · 2021Trial
- An RCT to Increase Breast and Colorectal Cancer Screening.American journal of preventive medicine · 2020Trial
- Correlates of Patient Intent and Preference on Colorectal Cancer Screening.American journal of preventive medicine · 2017Trial
- Trial
- Impact of Risk Assessment and Tailored versus Nontailored Risk Information on Colorectal Cancer Testing in Primary Care: A Randomized Controlled Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015Trial
- A Randomized Trial to Compare Alternative Educational Interventions to Increase Colorectal Cancer Screening in a Hard-to-Reach Urban Minority Population with Health Insurance.Journal of community health · 2015Trial
- Characteristics and Effectiveness of Patient Navigation Programs on Colorectal Cancer Screening and Follow-Up Colonoscopy Uptake: A Systematic Review.AJPM focus · 2026Review
- The role of patient navigation programs in early cancer care in Mexico: a multi-case qualitative study.The oncologist · 2025Article
- Effectiveness of a community health advisor colorectal cancer screening educational intervention on stool test completion in an African American primary care patient population: a pragmatic randomized controlled trial.BMC global and public health · 2025Article
- A socioecological taxonomy of determinants to colorectal cancer screening in black men: Insights from a mixed-methods systematic review.Preventive medicine reports · 2025Review
- Application of Patient Navigation in Colorectal Cancer Screening: A Scoping Review.Cancer management and research · 2025Review
Corrections and comments
- Commented on by
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe study aimed to determine the effect of preference-based tailored navigation on colorectal cancer (CRC) screening adherence and related outcomes among African Americans (AAs).
methodsWe conducted a randomized controlled trial that included 764 AA patients who were age 50 to 75 years, were eligible for CRC screening, and had received care through primary care practices in Philadelphia. Consented patients completed a baseline telephone survey and were randomized to either a Standard Intervention (SI) group (n = 380) or a Tailored Navigation Intervention (TNI) group (n = 384). The SI group received a mailed stool blood test kit plus colonoscopy instructions, and a reminder. The TNI group received tailored navigation (a mailed stool blood test kit or colonoscopy instructions based on preference, plus telephone navigation) and a reminder. A six-month survey and a 12-month medical records review were completed to assess screening adherence, change in overall screening preference, and perceptions about screening. Multivariable analyses were performed to assess intervention impact on outcomes.
resultsAt six months, adherence in the TNI group was statistically significantly higher than in the SI group (OR = 2.1, 95% CI = 1.5 to 2.9). Positive change in overall screening preference was also statistically significantly greater in the TNI group compared with the SI group (OR = 1.5, 95% CI = 1.0 to 2.3). There were no statistically significant differences in perceptions about screening between the study groups.
conclusionsTailored navigation in primary care is a promising approach for increasing CRC screening among AAs. Research is needed to determine how to maximize intervention effects and to test intervention impact on race-related disparities in mortality and survival.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.