ArticleMedicina oral, patologia oral y cirugia bucal2015
Mammary analogue secretory carcinoma (MASC) of salivary gland in four Mexican patients.
Article in Medicina oral, patologia oral y cirugia bucal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- Article
- A rare case of a mammary analog secretory carcinoma of the right submandibular gland.Journal of surgical case reports · 2025Article
- Non Indigenous Mammary Secretory Carcinoma of Parotid Gland - An Unusual Presentation.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Salivary gland secretory carcinoma presenting as a cervical soft tissue mass: a case report.Journal of medical case reports · 2024Review
- Diagnostic Utility of Expression Pattern of S100/Mammaglobin/SOX10/DOG 1 Immunohistochemistry in Differentiation of Secretory and Acinic Cell Carcinoma: A Systematic Review and Meta-Analysis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Mammary analogue secretory carcinoma of the salivary glands.Ecancermedicalscience · 2023Article
- NTRK3 mutation in secretory carcinoma of the parotid gland: A Case report.Clinical case reports · 2022Article
- Mammary analogue secretory carcinoma presenting with cervical lymphadenopathy: A rare case report with review of the literature.International journal of surgery case reports · 2022Article
- Mammary analogue secretory carcinoma in minor salivary gland.Einstein (Sao Paulo, Brazil) · 2022Article
- Secretory Carcinoma of the Oral Cavity: A Retrospective Case Series with Review of Literature.Head and neck pathology · 2021Review
- Usefulness of immunohistochemistry to distinguish between secretory carcinoma and acinic cell carcinoma in the salivary gland.Medical molecular morphology · 2021Article
- Article
- Mammary analogue secretory carcinoma of the minor salivary gland: report of two cases.International journal of clinical and experimental pathology · 2019Article
- Secretory Carcinoma of Minor Salivary Gland in Buccal Mucosa: A Case Report and Review of the Literature.Case reports in pathology · 2019Article
- Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available.Case reports in pathology · 2019Article
- Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature.Case reports in dentistry · 2019Article
- A case report of parotid mammary analogue secretory carcinoma and reviews.International journal of surgery case reports · 2019Article
- Secretory carcinoma: the eastern Canadian experience and literature review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2018Review
- Mammary analogue secretory carcinoma of salivary glands: diagnostic pitfall with distinct immunohistochemical profile and molecular features.Rare tumors · 2017Article
- Mammary analog secretory carcinoma, low-grade salivary duct carcinoma, and mimickers: a comparative study.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2015Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
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Abstract
The Clinco-pathological, immunohistochemical and molecular findings of four cases of Mammary Analogue Secretory Carcinoma (MASC) of salivary glands found in Mexico are described. The cases were extracted from 253 salivary gland tumors from a single institution in Mexico City. The 85 Candidates for initial selection were: low grade mucoepidermoid carcinoma (MEC) (N=70 ), Acinic cell cancinoma (AciCC) (N=14), papillary cystadenocarcinoma (N=1), and adenocarcinoma NOS (N=0). Tumors with some histological features consistent with MASC (N= 17, 6.7%) were studied by immunohistochemistry for mammaglobin, STAT5, and S-100 protein and four cases were positive (1.5%), thus the diagnosis of MASC was established, and these were submitted for molecular studies for ETV6-NTRK3. Fusion gene was demonstrated in three cases, two had been erroneously diagnosed as poorly granulated AciCC, and one as low grade MEC with microcystic pattern. Female gender predominated (3:1); one occurred in the parotid, two in minor salivary glands and one in the submaxillary gland; infiltrating borders, atypical mitosis and lymph node metastases were seen in the parotideal tumor. Two patients with major salivary gland tumors are alive and well at 10 and 20 months respectively, the two patients with minor salivary gland tumors are lost. It can be concluded that is important to think in MASC in poorly granulated AciCC and low grade MEC with microcystic pattern. Immunohistochemisty studies confirm the diagnosis, preferentially supported by molecular studies. MASC may follow aggressive behavior or transform into a high grade neoplasm.
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