ArticleCell stem cell2014
Sleeping beauty wakes up the clonal succession model for homeostatic hematopoiesis.
Article in Cell stem cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Redox Imbalance and Antioxidant Defenses Dysfunction: Key Contributors to Early Aging in Childhood Cancer Survivors.Antioxidants (Basel, Switzerland) · 2024Article
- Identification of Biochemical and Molecular Markers of Early Aging in Childhood Cancer Survivors.Cancers · 2021Article
- Hematopoiesis during Ontogenesis, Adult Life, and Aging.International journal of molecular sciences · 2021Review
- What do we know about the participation of hematopoietic stem cells in hematopoiesis?F1000Research · 2015Review
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
Abstract
Recently in Nature, Sun et al. (2014) used a sleeping beauty transposon system to demonstrate that natural hematopoiesis is sustained by the successive recruitment of thousands of clones that are mostly lineage restricted. These findings call into question whether homeostatic hematopoiesis is sustained by hematopoietic stem cells traditionally identified by transplantation.
Indexed as
Identifiers
25479744What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.