ArticlePloS one2014
Sexual orientation related differences in cortical thickness in male individuals.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of the neural correlates of sexual minority stress: towards an intersectional minority mosaic framework with implications for a future research agenda.European journal of psychotraumatology · 2022Pooled it
- Structural, Functional, and Metabolic Brain Differences as a Function of Gender Identity or Sexual Orientation: A Systematic Review of the Human Neuroimaging Literature.Archives of sexual behavior · 2021Pooled it
- White Matter Microstructure Among Straight and Gay Cisgender Men, Sao Praphet Song, and Straight Cisgender Women in Thailand.Human brain mapping · 2025Article
- A brief historic overview of sexual and gender diversity in neuroscience: past, present, and future.Frontiers in human neuroscience · 2024Article
- Carving the Biodevelopment of Same-Sex Sexual Orientation at Its Joints.Archives of sexual behavior · 2023Article
- Accurate machine learning prediction of sexual orientation based on brain morphology and intrinsic functional connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Cross-sex shifts in two brain imaging phenotypes and their relation to polygenic scores for same-sex sexual behavior: A study of 18,645 individuals from the UK Biobank.Human brain mapping · 2021Article
- Replication of Previous Findings? Comparing Gray Matter Volumes in Transgender Individuals with Gender Incongruence and Cisgender Individuals.Journal of clinical medicine · 2021Article
- Brain structure changes associated with sexual orientation.Scientific reports · 2021Article
- HIV-Associated Structural and Functional Brain Alterations in Homosexual Males.Frontiers in neurology · 2021Article
- Male sexual orientation, gender nonconformity, and neural activity during mental rotations: an fMRI study.Scientific reports · 2020Article
- Interactive effects of gender and sexual orientation on cortical thickness, surface area and gray matter volume: a structural brain MRI study.Quantitative imaging in medicine and surgery · 2020Article
- Possible Neurobiological Underpinnings of Homosexuality and Gender Dysphoria.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Sex Hormones and Gender Role Relate to Gray Matter Volumes in Sexually Dimorphic Brain Areas.Frontiers in neuroscience · 2019Article
- Cortical brain structure and sexual orientation in adult females with bipolar disorder or attention deficit hyperactivity disorder.Brain and behavior · 2018Article
- Transsexualism: A Different Viewpoint to Brain Changes.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2018Review
- Cerebral sex dimorphism and sexual orientation.Human brain mapping · 2018Article
- Multimodal MRI suggests that male homosexuality may be linked to cerebral midline structures.PloS one · 2018Article
- Structural connections in the brain in relation to gender identity and sexual orientation.Scientific reports · 2017Article
- A Review of the Status of Brain Structure Research in Transsexualism.Archives of sexual behavior · 2016Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous neuroimaging studies demonstrated sex and also sexual orientation related structural and functional differences in the human brain. Genetic information and effects of sex hormones are assumed to contribute to the male/female differentiation of the brain, and similar effects could play a role in processes influencing human's sexual orientation. However, questions about the origin and development of a person's sexual orientation remain unanswered, and research on sexual orientation related neurobiological characteristics is still very limited. To contribute to a better understanding of the neurobiology of sexual orientation, we used magnetic resonance imaging (MRI) in order to compare regional cortical thickness (Cth) and subcortical volumes of homosexual men (hoM), heterosexual men (heM) and heterosexual women (heW). hoM (and heW) had thinner cortices primarily in visual areas and smaller thalamus volumes than heM, in which hoM and heW did not differ. Our results support previous studies, which suggest cerebral differences between hoM and heM in regions, where sex differences have been reported, which are frequently proposed to underlie biological mechanisms. Thus, our results contribute to a better understanding of the neurobiology of sexual orientation.
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Registered trials
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