ArticlePloS one2014
Long term molecular epidemiology of methicillin-susceptible Staphylococcus aureus bacteremia isolates in Sweden.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Dissemination and Molecular Characterization ofBioMed research international · 2017Trial
- Impact of sex on clinical management and mortality in community-onset Staphylococcus aureus bacteraemia: a retrospective study.BMC infectious diseases · 2026Article
- Occurrence, variability and evolutionary relations of efflux pump determinants across five pathogenicFrontiers in pharmacology · 2026Article
- Reliability of disc diffusion testing and molecular epidemiology of penicillin-susceptible Staphylococcus aureus bacteraemia.The Journal of antimicrobial chemotherapy · 2025Article
- Staphylococcus aureus From Prosthetic Joint Infections and Blood Cultures Display the Same Genetic Background.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025Article
- Historic methicillin-resistant Staphylococcus aureus: expanding current knowledge using molecular epidemiological characterization of a Swiss legacy collection.Genome medicine · 2024Article
- Characterisation of aPathogens (Basel, Switzerland) · 2023Article
- Vancomycin Resistance inMicroorganisms · 2022Review
- RETRACTED: An Overview of Antimicrobial Stewardship Optimization: The Use of Antibiotics in Humans and Animals to Prevent Resistance.Antibiotics (Basel, Switzerland) · 2022Review
- Description of Methicillin-Susceptible Staphylococcus aureus Clonal Complex 30 Related to the Pandemic Phage Type 80/81 Isolated from Patients in Three Tertiary Hospitals in Jos, North Central Nigeria.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022Article
- Comparison of Molecular Characteristics Between Methicillin-Resistant and -SusceptibleInfection and drug resistance · 2022Article
- Genomic analyses ofMicrobial genomics · 2020Article
- Characterization of a New Staphylococcus aureus Kayvirus Harboring a Lysin Active against Biofilms.Viruses · 2018Article
- A review on nanosystems as an effective approach against infections ofInternational journal of nanomedicine · 2018Review
- Reduced pro-inflammatory responses to Staphylococcus aureus bloodstream infection and low prevalence of enterotoxin genes in isolates from patients on haemodialysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Population-based epidemiology of Staphylococcus aureus bloodstream infection: clonal complex 30 genotype is associated with mortality.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Article
- Omics Approaches for the Study of Adaptive Immunity toProteomes · 2016Review
- Article
- Healthcare Associated Infections of Methicillin-Resistant Staphylococcus aureus: A Case-Control-Control Study.PloS one · 2015Article
- An assessment on DNA microarray and sequence-based methods for the characterization of methicillin-susceptible Staphylococcus aureus from Nigeria.Frontiers in microbiology · 2015Article
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5 authors.
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Abstract
Staphylococcus aureus is one of the major pathogens that causes bacteremia; therefore, it is important to understand the long-term molecular epidemiology of S. aureus bacteremia infections. In particular, little is known about the population structure of methicillin-sensitive S. aureus (MSSA) compared to that of methicillin-resistant S. aureus. We investigated potential changes in the MSSA molecular epidemiology in Örebro County, Sweden, from 1980 through 2010. 400 MSSA bacteremia isolates, the first 100 isolated each decade from 1980 through 2010, were retrospectively identified and analyzed regarding assignment to clonal complexes (CCs), presence of virulence genes and antibiotic resistant determinants with DNA microarray-based genotyping. 24 different CCs were identified. Most isolates (80%) belonged to 6 predominant lineages. Of those, the number of isolates assigned to CC5 and CC15 increased, and those assigned to CC8, CC25, and CC30 decreased. The most prevalent clone, CC45, did not show a significant change in prevalence during the study period. A change in prevalence was observed for some of the virulence genes, mainly attributed with their association to certain CCs. With the exception of the common blaZ gene (encoding penicillinase), antibiotic resistance genes were only sporadically detected. In conclusion, the MSSA population structure was genetically diverse. We observed decadal changes in assignments to five predominant clones, and corresponding changes in the prevalence of some virulence genes linked to CC affiliation. In light of the restrictive antibiotics prescriptions and extensive infection control procedures in Sweden, antibiotic resistance genes were rarely detected and their prevalence unaffected during the study period.
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