ArticlePloS one2014
Intraindividual variability in inhibitory function in adults with ADHD--an ex-Gaussian approach.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Differences in Ex-Gaussian Parameters from Response Time Distributions Between Individuals with and Without Attention Deficit/Hyperactivity Disorder: A Meta-analysis.Neuropsychology review · 2024Pooled it
- Beyond Neural Noise: Critical Dynamics Predict Slower Reaction Times in Adults With and Without ADHD.bioRxiv : the preprint server for biology · 2026Article
- Shared genetic etiology between ADHD, task-related behavioral measures and brain activation during response inhibition in a youth ADHD case-control study.European archives of psychiatry and clinical neuroscience · 2024Article
- The effect of background sounds on mind wandering.Psychological research · 2023Article
- Time Perception in Adult ADHD: Findings from a Decade-A Review.International journal of environmental research and public health · 2023Review
- Stability of Attention Performance of Adults with ADHD over Time: Evidence from Repeated Neuropsychological Assessments in One-Month Intervals.International journal of environmental research and public health · 2022Article
- Ahead of the (ROC) Curve: A Statistical Approach to Utilizing Ex-Gaussian Parameters of Reaction Time in Diagnosing ADHD Across Three Developmental Periods.Journal of the International Neuropsychological Society : JINS · 2022Article
- Automated Classification of Cognitive Workload Levels Based on Psychophysiological and Behavioural Variables of Ex-Gaussian Distributional Features.Brain sciences · 2022Article
- Event-related brain-oscillatory and ex-Gaussian markers of remission and persistence of ADHD.Psychological medicine · 2022Article
- Attention Networks in ADHD Adults after Working Memory Training with a DualBrain sciences · 2020Article
- Are model parameters linked to processing stages? An empirical investigation for the ex-Gaussian, ex-Wald, and EZ diffusion models.Psychological research · 2020Article
- Intact Stimulus-Response Conflict Processing in ADHD-Multilevel Evidence and Theoretical Implications.Journal of clinical medicine · 2020Article
- The Quantified Behavioral Test-A Confirmatory Test in the Diagnostic Process of Adult ADHD?Frontiers in psychiatry · 2020Article
- Basic processes as foundations of cognitive impairment in adult ADHD.Journal of neural transmission (Vienna, Austria : 1996) · 2019Article
- Abnormalities in hubs location and nodes centrality predict cognitive slowing and increased performance variability in first-episode schizophrenia patients.Scientific reports · 2019Article
- Electrophysiological Correlates of Response Time Variability During a Sustained Attention Task.Frontiers in human neuroscience · 2019Article
- Article
- Non-Gaussian Distributional Analyses of Reaction Times (RT): Improvements that Increase Efficacy of RT Tasks for Describing Cognitive Processes.Neuropsychology review · 2018Review
- An investigation of intra-individual variability in children with fetal alcohol spectrum disorder (FASD).Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2018Article
- Analysis of Attention Subdomains in Obstructive Sleep Apnea Patients.Frontiers in psychiatry · 2018Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAttention deficit disorder (ADHD) is commonly associated with inhibitory dysfunction contributing to typical behavioral symptoms like impulsivity or hyperactivity. However, some studies analyzing intraindividual variability (IIV) of reaction times in children with ADHD (cADHD) question a predominance of inhibitory deficits. IIV is a measure of the stability of information processing and provides evidence that longer reaction times (RT) in inhibitory tasks in cADHD are due to only a few prolonged responses which may indicate deficits in sustained attention rather than inhibitory dysfunction. We wanted to find out, whether a slowing in inhibitory functioning in adults with ADHD (aADHD) is due to isolated slow responses.
methodsComputing classical RT measures (mean RT, SD), ex-Gaussian parameters of IIV (which allow a better separation of reaction time (mu), variability (sigma) and abnormally slow responses (tau) than classical measures) as well as errors of omission and commission, we examined response inhibition in a well-established GoNogo task in a sample of aADHD subjects without medication and healthy controls matched for age, gender and education.
resultsWe did not find higher numbers of commission errors in aADHD, while the number of omissions was significantly increased compared with controls. In contrast to increased mean RT, the distributional parameter mu did not document a significant slowing in aADHD. However, subjects with aADHD were characterized by increased IIV throughout the entire RT distribution as indicated by the parameters sigma and tau as well as the SD of reaction time. Moreover, we found a significant correlation between tau and the number of omission errors.
conclusionsOur findings question a primacy of inhibitory deficits in aADHD and provide evidence for attentional dysfunction. The present findings may have theoretical implications for etiological models of ADHD as well as more practical implications for neuropsychological testing in aADHD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.