ArticlePloS one2014
Human growth and body weight dynamics: an integrative systems model.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Modeling the dynamics of human starvation: incorporating lessons from famines past and present.Journal of public health policy · 2026Review
- Modeling Health and Economic Outcomes of Eliminating Sex Disparities in Youth Physical Activity.JAMA network open · 2024Article
- Benefits of Meeting the Healthy People 2030 Youth Sports Participation Target.American journal of preventive medicine · 2024Article
- Health and Economic Value of Eliminating Socioeconomic Disparities in US Youth Physical Activity.JAMA health forum · 2024Article
- A long-acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model.Clinical and translational science · 2023Article
- Proposal of a Mathematical Model to Monitor Body Mass over Time in Subjects on a Diet.Nutrients · 2022Article
- The Impact of a Place-Tailored Digital Health App Promoting Exercise Classes on African American Women's Physical Activity and Obesity: Simulation Study.Journal of medical Internet research · 2022Article
- The impact of reducing the frequency of night feeding on infant BMI.Pediatric research · 2022Article
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- Novel type of references for weight aligned for onset of puberty - using the QEPS growth model.BMC pediatrics · 2021Article
- Can following formula-feeding recommendations still result in infants who are overweight or have obesity?Pediatric research · 2020Article
- Using Simulation Modeling to Guide the Design of the Girl Scouts Fierce & Fit Program.Obesity (Silver Spring, Md.) · 2020Article
- The Impact of Following Solid Food Feeding Guides on BMI Among Infants: A Simulation Study.American journal of preventive medicine · 2019Article
- Dynamics of intervention adoption, implementation, and maintenance inside organizations: The case of an obesity prevention initiative.Social science & medicine (1982) · 2019Article
- Simulating the Impact of Sugar-Sweetened Beverage Warning Labels in Three Cities.American journal of preventive medicine · 2018Article
- Dynamics of Implementation and Maintenance of Organizational Health Interventions.International journal of environmental research and public health · 2017Article
- A time-varying biased random walk approach to human growth.Scientific reports · 2017Article
- Translational Modeling to Guide Study Design and Dose Choice in Obesity Exemplified by AZD1979, a Melanin-concentrating Hormone Receptor 1 Antagonist.CPT: pharmacometrics & systems pharmacology · 2017Article
- Using Agent-Based Models to Develop Public Policy about Food Behaviours: Future Directions and Recommendations.Computational and mathematical methods in medicine · 2017Review
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Quantifying human weight and height dynamics due to growth, aging, and energy balance can inform clinical practice and policy analysis. This paper presents the first mechanism-based model spanning full individual life and capturing changes in body weight, composition and height. Integrating previous empirical and modeling findings and validated against several additional empirical studies, the model replicates key trends in human growth including A) Changes in energy requirements from birth to old ages. B) Short and long-term dynamics of body weight and composition. C) Stunted growth with chronic malnutrition and potential for catch up growth. From obesity policy analysis to treating malnutrition and tracking growth trajectories, the model can address diverse policy questions. For example I find that even without further rise in obesity, the gap between healthy and actual Body Mass Indexes (BMIs) has embedded, for different population groups, a surplus of 14%-24% in energy intake which will be a source of significant inertia in obesity trends. In another analysis, energy deficit percentage needed to reduce BMI by one unit is found to be relatively constant across ages. Accompanying documented and freely available simulation model facilitates diverse applications customized to different sub-populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.