ArticleInternational journal of genomics2014
Comparison of Metabolic Network between Muscle and Intramuscular Adipose Tissues in Hanwoo Beef Cattle Using a Systems Biology Approach.
Article in International journal of genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Article
- Imbalance between skeletal muscle and intermuscular fat predicts treatment failure in Crohn's disease: an imaging biomarker for risk stratification.Annals of medicine · 2025Article
- Dietary Fermentation withInternational journal of molecular sciences · 2025Article
- Association of sex-specific abdominal adipose tissue with WHO/ISUP grade in clear cell renal cell carcinoma.Insights into imaging · 2023Article
- RNA-Seq Analysis Identifies Differentially Expressed Genes in theInternational journal of molecular sciences · 2022Article
- Comparative Genome-Wide Alternative Splicing Analysis of Longissimus Dorsi Muscles Between Japanese Black (Wagyu) and Chinese Red Steppes Cattle.Frontiers in veterinary science · 2021Article
- Article
- Comparison of characteristics of long noncoding RNA in Hanwoo according to sex.Asian-Australasian journal of animal sciences · 2020Article
- Intermuscular adipose tissue directly modulates skeletal muscle insulin sensitivity in humans.American journal of physiology. Endocrinology and metabolism · 2019Article
- Gene expression of Hanwoo satellite cell differentiation in longissimus dorsi and semimembranosus.BMC genomics · 2019Article
- Comparison of long noncoding RNA between muscles and adipose tissues inAnimal cells and systems · 2019Article
- Assessing genetic architecture and signatures of selection of dual purpose Gir cattle populations using genomic information.PloS one · 2018Article
- Gene expression profile of intramuscular muscle in Nellore cattle with extreme values of fatty acid.BMC genomics · 2016Article
- Validation of Single Nucleotide Polymorphisms Associated with Carcass Traits in a Commercial Hanwoo Population.Asian-Australasian journal of animal sciences · 2016Article
- Multi-omic data integration and analysis using systems genomics approaches: methods and applications in animal production, health and welfare.Genetics, selection, evolution : GSE · 2016Review
- Genome-wide association and genomic prediction of breeding values for fatty acid composition in subcutaneous adipose and longissimus lumborum muscle of beef cattle.BMC genetics · 2015Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interrelationship between muscle and adipose tissues plays a major role in determining the quality of carcass traits. The objective of this study was to compare metabolic differences between muscle and intramuscular adipose (IMA) tissues in the longissimus dorsi (LD) of Hanwoo (Bos taurus coreanae) using the RNA-seq technology and a systems biology approach. The LD sections between the 6th and 7th ribs were removed from nine (each of three cows, steers, and bulls) Hanwoo beef cattle (carcass weight of 430.2 ± 40.66 kg) immediately after slaughter. The total mRNA from muscle, IMA, and subcutaneous adipose and omental adipose tissues were isolated and sequenced. The reads that passed quality control were mapped onto the bovine reference genome (build bosTau6), and differentially expressed genes across tissues were identified. The KEGG pathway enrichment tests revealed the opposite direction of metabolic regulation between muscle and IMA. Metabolic gene network analysis clearly indicated that oxidative metabolism was upregulated in muscle and downregulated in IMA. Interestingly, pathways for regulating cell adhesion, structure, and integrity and chemokine signaling pathway were upregulated in IMA and downregulated in muscle. It is thus inferred that IMA may play an important role in the regulation of development and structure of the LD tissues and muscle/adipose communication.
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Registered trials
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