ArticlePsychiatry journal2014
Sex differences and menstrual cycle phase-dependent modulation of craving for cigarette: an FMRI pilot study.
Article in Psychiatry journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Parameter Space and Potential for Biomarker Development in 25 Years of fMRI Drug Cue Reactivity: A Systematic Review.JAMA psychiatry · 2024Pooled it
- Effects of Biperiden (Cholinergic Muscarinic m1/m4 Receptor Antagonist) on Craving Nicotine: A Proof-Of-Concept Clinical Study.European addiction research · 2025Trial
- Progesterone Increases Nicotine Withdrawal and Anxiety in Male but Not Female Smokers During Brief Abstinence.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Trial
- Modulation of High-Frequency rTMS on Reward Circuitry in Individuals with Nicotine Dependence: A Preliminary fMRI Study.Neural plasticity · 2024Article
- A systematic review of sex/gender differences in the multi-dimensional neurobiological mechanisms in addiction and their relevance to impulsivity.Current addiction reports · 2023Article
- Methodological approach for an integrated female-specific study of anxiety and smoking comorbidity.Frontiers in psychiatry · 2023Article
- Sex Differences in the Association of Cigarette Craving With Insula Structure.The international journal of neuropsychopharmacology · 2021Article
- Influence of the natural hormonal milieu on brain and behavior in women who smoke cigarettes: Rationale and methodology.Contemporary clinical trials communications · 2021Article
- Success Factors for Tobacco Smoking Cessation Among Korean Female College Student Smokers.Journal of community health · 2020Article
- Retrospective and prospective assessments of gambling-related behaviors across the female menstrual cycle.Journal of behavioral addictions · 2019Article
- Sex/Gender Differences in Cotinine Levels Among Daily Smokers in the Pennsylvania Adult Smoking Study.Journal of women's health (2002) · 2017Article
- Multi-site exploration of sex differences in brain reactivity to smoking cues: Consensus across sites and methodologies.Drug and alcohol dependence · 2017Article
- Severity of dependence modulates smokers' functional connectivity in the reward circuit: a preliminary study.Psychopharmacology · 2016Article
- Ovarian hormones, menstrual cycle phase, and smoking: a review with recommendations for future studies.Current addiction reports · 2016Article
- Sex differences in resting state brain function of cigarette smokers and links to nicotine dependence.Experimental and clinical psychopharmacology · 2015Article
- Cigarette Cravings, Impulsivity, and the Brain.Frontiers in psychiatry · 2015Review
- Is It Important to Consider Sex and Gender in Neurocognitive Studies?Frontiers in psychiatry · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While overall more men than women smoke cigarettes, women and girls take less time to become dependent after initial use and have more difficulties quitting the habit. One of the factors contributing to these differences may be that women crave cigarettes more than men and that their desire to smoke is influenced by hormonal fluctuations across the menstrual cycle. Therefore, the purpose of the present study was twofold: (a) to examine potential sex/gender differences in functional neuroanatomy of craving and to (b) delineate neural correlates of cigarette cravings in women across their menstrual cycle. Fifteen tobacco-smoking men and 19 women underwent a functional MRI during presentation of neutral and smoking-related images, known to elicit craving. Women were tested twice: once during early follicular phase and once during midluteal phase of their menstrual cycle. The analysis did not reveal any significant sex differences in the cerebral activations associated with craving. Nevertheless, the pattern of activations in women varied across their menstrual cycle with significant activations in parts of the frontal, temporal, and parietal lobe, during follicular phase, and only limited activations in the right hippocampus during the luteal phase.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.