Evidence map›Paper›PMID 25478419›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Vitamin d levels in children with bronchial asthma.

A R Somashekar, Ashwini B Prithvi, M N Vanitha Gowda

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04461665 (Effects of Vitamin D Supplementation on Immune Function in Infants), which is not on this map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04461665 nacompletednot on this mapstarted 2015, after this paper: background citation

Effects of Vitamin D Supplementation on Immune Function in Infants

TypeinterventionalSponsorShih Chien UniversityRan2015 to 2016Enrolled59ConditionsVitamin D DeficiencyArmsvitamin D
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. The impact of vitamin D on asthmatic human airway smooth muscle.Expert review of respiratory medicine · 2016
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

A R SomashekarProfessor, Department of Paediatrics, M S Ramaiah Medical College and Hospitals , Bangalore, India .
Ashwini B PrithviIntern, Department of Paediatrics, M S Ramaiah Medical College and Hospitals , Bangalore, India .
M N Vanitha GowdaAssociate Professor, Department of Biochemistry, M S Ramaiah Medical College and Hospitals , Bangalore, India .
M.S. Ramaiah Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBronchial Asthma is a common chronic inflammatory disorder of the airways in childhood. Vitamin-D, required for bone mineralization, is also a potent immune system regulator having a potential role in various allergic diseases. This study was undertaken to determine the difference in serum levels of Vitamin-D in asthmatic children and to determine the association between vitamin-D and asthma in children. MATERIALS AND

methodsThis cross-sectional study included 88 (44 asthmatic children and 44 healthy controls) children aged between 5 and 13 y. Serum 25-hydroxy vitamin-D levels were determined and compared between the two groups. The association between vitamin-D levels and lung function was studied in the asthmatic children.

resultsSerum vitamin-D level was significantly lower in asthmatic children than in control group and in the asthmatic group, vitamin-D levels had a significant positive correlation with FEV1% and FEV1/FVC%.

conclusionVitamin-D deficiency is highly prevalent in asthmatic children and is associated with airway limitation.

Indexed as

Airway limitationAsthmaChildrenLung functionVitamin-D

Identifiers

PMID25478419
PMCPMC4253237
OpenAlexW2004007077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.