Evidence map›Paper›PMID 25478409›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

The effect of epidural analgesia on labour, mode of delivery and neonatal outcome in nullipara of India, 2011-2014.

Dipti Agrawal, Bela Makhija, Manjeet Arora, Arpana Haritwal, Pavan Gurha

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Endorphins, Sexuality, and Reproduction.Advances in neurobiology · 2024
    Article
  4. Article
  5. Article
  6. Observational
  7. Effects of Labor Epidural Analgesia on Short Term Neonatal Morbidity.International journal of women's health · 2020
    Article
  8. Epidural Analgesia and Back Pain after Labor.Medicina (Kaunas, Lithuania) · 2019
    Article
  9. Epidural Analgesia and Neonatal Morbidity: A Retrospective Cohort Study.International journal of environmental research and public health · 2018
    Article
  10. Effects of Epidural Labour Analgesia in Mother and Foetus.Journal of obstetrics and gynaecology of India · 2018
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dipti AgrawalResident, Department of Obstetrics and Gynaecology, Batra Hospital and Medical Research Centre , Tughlakabad Institutional Area, New Delhi, India .
Bela MakhijaSenior Consultant, Department of Obstetrics and Gynaecology, Batra Hospital and Medical Research Centre , Tughlakabad Institutional Area, New Delhi, India .
Manjeet AroraSenior Consultant, Department of Obstetrics and Gynaecology, Batra Hospital and Medical Research Centre , Tughlakabad Institutional Area, New Delhi, India .
Arpana HaritwalConsultant, Department of Obstetrics and Gynaecology, Batra Hospital and Medical Research Centre , Tughlakabad Institutional Area, New Delhi, India .
Pavan GurhaHead of Department, Department of Anaesthesia & Critical Care, Batra Hospital and Medical Research Centre , Tughlakabad Institutional Area, New Delhi, India .
Batra Hospital and Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study aimed to evaluate the effect of ropivacaine epidural analgesia on duration and outcome of labour in nulliparous parturients of India with parturient not receiving any analgesia. SETTINGS AND

designOne hundred and twenty nulliparous parturient in established labour at full term with a singleton vertex presentation were assigned to the study. Parturients who request epidural analgesia were allocated in the epidural group (n=60), whereas those not enthusiastic to labour analgesia were allocated in the control group (n=60). MATERIALS AND

methodsEpidural analgesia was provided by a bolus injection of 10 ml of ropivacaine 0.2% and 50μg fentanyl and maintained by using a continuous infusion of ropivacaine 0.1% with fentanyl 2μl/ml at a 10ml/hour rate. The outcomes were duration of labour, incidence of cesarean sections and instrumental vaginal delivery and neonatal outcome. STATISTICAL ANALYSIS USED: Statistical analysis was conducted using unpaired student t-test and chi-square test as required. All tests of significance were performed using two-tailed probability tests. Differences were considered significant when p-value was <0.05.

resultsThe two groups were comparable in terms of socio-demographic data. The mean duration of first stage of labour was shorter in epidural group (4.83 ± 1.59 h) compared with control group (5.48 ± 1.56 h) while the duration of second stage of labour was prolong in epidural group (33.13 ± 12.78 min) as compared to control (27.53 ± 11.73 min). Instrumental vaginal or caesarean delivery rate did not increase in the epidural group. The APGAR scores at 5 min were statistically similar in both groups.

conclusionEpidural analgesia by ropivacaine in Indian nulliparous resulted in shorter duration of first stage and prolongs duration of second stage of labour compared with parturients without analgesia; however, instrumental vaginal or caesarean delivery rate does not increase in the epidural group.

Indexed as

Epidural analgesiaLabourNulliparousParturientRopivacaine

Identifiers

PMID25478409
PMCPMC4253227
OpenAlexW74612290

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.