Evidence map›Paper›PMID 25478371›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Smear Conversion, Treatment Outcomes and the Time of Default in Registered Tuberculosis Patients on RNTCP DOTS in Puducherry, Southern India.

Kavita Vasudevan, Niranjana Jayakumar, Dhivyalakshmi Gnanasekaran

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Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

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11citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. A systematic review of clinical outcomes on the WHO Category II retreatment regimen for tuberculosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2018
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Predictors of tuberculosis treatment outcomes among a retrospective cohort in rural, Central India.Journal of clinical tuberculosis and other mycobacterial diseases · 2018
    Article
  9. Article
  10. Article
  11. Article
4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Kavita VasudevanAssociate Professor, Department of Community Medicine, Indira Gandhi Medical College , Kathirkamam, Pondicherry, India .
Niranjana JayakumarResident, Department of Community Medicine, Indira Gandhi Medical College , Kathirkamam, Pondicherry, India .
Dhivyalakshmi GnanasekaranResident, Department of Community Medicine, Indira Gandhi Medical College , Kathirkamam, Pondicherry, India .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRevised National Tuberculosis Control Programme (RNTCP) in India has achieved improved cure rates.

objectivesThis study describes the achievements under RNTCP in terms of conversion rates, treatment outcomes and pattern of time of default in patients on directly observed short-course treatment for Tuberculosis in Puducherry, Southern India. SETTINGS: Retrospective cohort study; Tuberculosis Unit in District Tuberculosis Centre, Puducherry, India. MATERIALS AND

methodsCohort analysis of patients of registered at the Tuberculosis Unit during 1(st) and 2(nd) quarter of the year 2011. Details about sputum conversion, treatment outcome and time of default were obtained from the tuberculosis register. STATISTICAL ANALYSIS: Kaplan-Meier plots & log rank tests.

resultsRNTCP targets with respect to success rate (85.7%), death rate (2.7%) and failure rate (2.1%) in new cases have been achieved but the sputum conversion rate (88%) and default rate (5.9%) targets have not been achieved. The overall default rate for all registered TB patients was 7.4%; significantly higher in category II. In retreatment cases registered as treatment after default, the default rate was high (9%). The cumulative default rate; though similar in the initial two months of treatment; was consistently higher in category II as compared to that in category I. Nearly 40% of all defaulters interrupted treatment between the second and fourth month after treatment initiation.

conclusionDefaulting from treatment is more common among the retreatment cases and usually occurs during the transition phase from intensive phase to continuation phase.

Indexed as

DefaultDirectly observed treatment-short course (DOTS)OutcomeSputum conversion

Identifiers

PMID25478371
PMCPMC4253189

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