Evidence map›Paper›PMID 25478333›Full record

ArticleJournal of clinical and diagnostic research : JCDR2014

Cold pressor response in high landers versus low landers.

Jagdish Narayan, Archana Ghildiyal, Manish Goyal, Dileep Verma, Shraddha Singh, Sunita Tiwari

Abstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Contrast-enhanced ultrasonography reveals a lower cortical perfusion and a decreased renal flow reserve in hypertensive patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  2. An Exaggerated Rise in Pulmonary Artery Pressure in a High-Altitude Dweller during the Cold Season.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jagdish NarayanAssistant Professor, Department of Physiology, King George's Medical University , Lucknow, Uttar Pradesh, India .
Archana GhildiyalAssociate Professor, Department of Physiology, King George's Medical University , Lucknow, Uttar Pradesh, India .
Manish GoyalAssistant Professor, Department of Physiology, All India Institute of Medical Sciences , Bhubaneswar, Odisha, India .
Dileep VermaAssociate Professor, Department of Physiology, King George's Medical University , Lucknow, Uttar Pradesh, India .
Shraddha SinghProfessor, Department of Physiology, King George's Medical University , Lucknow, Uttar Pradesh, India .
Sunita TiwariProfessor, Department of Physiology, King George's Medical University , Lucknow, Uttar Pradesh, India .

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNative high landers face two main environmental challenges i.e. hypobaric hypoxia and low ambient temperatures. Both factors contribute to increased sympathetic stimulation and increased blood pressure. Despite these challenges, subjects living at high altitude have lower systolic and diastolic pressures as compared to subjects living in plains. Present study investigated cold pressor test (CPT) which is a potential predictor of future hypertension in high landers and low landers Materials and Methods: Vascular reactivity in terms of changes in systolic and diastolic blood pressure and heart rate in response to cold pressor test has been compared in high lander (n=45) and low lander (n=46) population.

resultsSystolic and diastolic blood pressure changes and heart rate changes with cold pressor test are lower in high landers as compared to low landers. Females in both the groups in general exhibited greater cold pressor response than males.

conclusionHypo-reactive cold pressor test is due to higher parasympathetic tone and lower sympathetic tone. Decreased cold pressor response in high landers reflects another adaptive modulation of sympatho-vagal activity that enables them to stay in hypobaric atmosphere and lower temperatures without undue autonomic stress.

Indexed as

AltitudeAutonomicCPTHypertensionParasympatheticSympathetic

Identifiers

PMID25478333
PMCPMC4253151

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