ArticleBMJ open respiratory research2014
Childhood adversity and asthma prevalence: evidence from 10 US states (2009-2011).
Article in BMJ open respiratory research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Adverse childhood experience and asthma onset: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2015Pooled it
- Adverse childhood experiences and hypertension: examining the roles of depressive symptoms and cardiometabolic dysregulations based on CHARLS data.Frontiers in public health · 2025Article
- SCD and asthma comorbidity: the potential role of adverse childhood experiences.Journal of sickle cell disease · 2025Article
- The effects of violence and related stress on asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024Review
- Article
- Adverse Events during Adulthood, Child Maltreatment, and Asthma among British Adults in the UK Biobank.Annals of the American Thoracic Society · 2023Article
- Linking specific biological signatures to different childhood adversities: findings from the HERO project.Pediatric research · 2023Article
- Violent Victimization During Childhood in the United States: Associations With Revictimization and Health.Violence and victims · 2023Article
- Structural Racism and the Social Determinants of Health in Asthma.Advances in experimental medicine and biology · 2023Article
- Child maltreatment, anxiety and depression, and asthma among British adults in the UK Biobank.The European respiratory journal · 2022Article
- Child maltreatment and asthma.Pediatric pulmonology · 2022Review
- Addressing the biological embedding of early life adversities (ELA) among adults through mindfulness: Proposed mechanisms and review of converging evidence.Neuroscience and biobehavioral reviews · 2022Review
- Structural racism and its pathways to asthma and atopic dermatitis.The Journal of allergy and clinical immunology · 2021Review
- Adverse Childhood Experiences and Association With Pediatric Asthma Severity in the 2016-2017 National Survey of Children's Health.Academic pediatrics · 2021Article
- Intersections of Adverse Childhood Experiences, Race and Ethnicity and Asthma Outcomes: Findings from the Behavioral Risk Factor Surveillance System.International journal of environmental research and public health · 2020Article
- Contrasting cumulative risk and multiple individual risk models of the relationship between Adverse Childhood Experiences (ACEs) and adult health outcomes.BMC medical research methodology · 2020Article
- Structural and Social Determinants of Health in Asthma in Developed Economies: a Scoping Review of Literature Published Between 2014 and 2019.Current allergy and asthma reports · 2020Article
- Adverse childhood experiences and chronic lung diseases in adulthood: a systematic review and meta-analysis.European journal of psychotraumatology · 2020Review
- Article
- Adult health burden and costs in California during 2013 associated with prior adverse childhood experiences.PloS one · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundExisting evidence on stress and asthma prevalence has disproportionately focused on pregnancy and postpregnancy early life stressors, largely ignoring the role of childhood adversity as a risk factor. Childhood adversity (neglect, stressful living conditions and maltreatment) may influence asthma prevalence through mechanisms on the hypothalamic-pituitary axis.
methodsData from the Center for Disease Control's (CDC's) Behavioral Risk Factor Surveillance System (BRFSS) surveys were used to examine cross-sectional associations of adverse childhood experiences (ACE) with lifetime and current asthma prevalence. Information on childhood adversity was available from 84 786 adult respondents in 10 US states. Poisson regression models (with robust SE) were used to estimate prevalence ratios (PRs) relating overall ACE score and dimensions of exposure ACE to asthma prevalence, adjusting for socioeconomic status.
resultsGreater ACE was associated with a higher prevalence of asthma (adjusted PRcat 4=1.78 (95% CI 1.69 to 1.87), adjusted PRcat 1=1.21 (95% CI 1.16 to 1.27)). Reported experiences of sexual abuse (adjusted PR=1.48* (1.42 to 1.55)) and physical abuse (adjusted PR=1.38* (1.33 to 1.43)) were associated with a higher asthma prevalence. No clear socioeconomic gradient was noted, but those reporting lowest education and income levels reported high rates of asthma and adversity. Sensitivity analyses indicated that ACE exposures were interrelated.
conclusionsReport of childhood adversity predicts asthma prevalence among US adults. Frameworks for asthma prevention need to recognise and integrate aspects related to childhood adversity. Further investigation into specific time periods of exposure would provide meaningful inferences for interventions.
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