ArticleBMJ open respiratory research2014
Using a non-invasive assessment of lung injury in a murine model of acute lung injury.
Article in BMJ open respiratory research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 29 citations in OpenAlex.
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- Clarithromycin Inhibits Pneumolysin Production via Downregulation ofMicrobiology spectrum · 2021Article
- IL-33-mediated Eosinophilia Protects against Acute Lung Injury.American journal of respiratory cell and molecular biology · 2021Article
- Effect of exercise training in rats exposed to chronic hypoxia: Application for Monge's disease.Physiological reports · 2021Article
- CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis.Frontiers in pharmacology · 2021Article
- High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier.eLife · 2020Article
- Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis.American journal of respiratory cell and molecular biology · 2020Article
- Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis.PloS one · 2020Article
- Pneumolysin Induces 12-Lipoxygenase-Dependent Neutrophil Migration duringJournal of immunology (Baltimore, Md. : 1950) · 2020Article
- Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse.American journal of physiology. Lung cellular and molecular physiology · 2017Article
- Vitamin D Deficiency in Human and Murine Sepsis.Critical care medicine · 2017Article
- Effect of anti-podoplanin antibody administration during lipopolysaccharide-induced lung injury in mice.BMJ open respiratory research · 2017Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
Arterial oxygen saturation has not been assessed sequentially in conscious mice as a direct consequence of an in vivo murine model of acute lung injury. Here, we report daily changes in arterial oxygen saturation and other cardiopulmonary parameters by using infrared pulse oximetry following intratracheal lipopolysaccharide (IT-LPS) for up to 9 days, and following IT-phosphate buffered saline up to 72 h as a control. We show that arterial oxygen saturation decreases, with maximal decline at 96 h post IT-LPS. Blood oxygen levels negatively correlate with 7 of 10 quantitative markers of murine lung injury, including neutrophilia and interleukin-6 expression. This identifies infrared pulse oximetry as a method to non-invasively monitor arterial oxygen saturation following direct LPS instillations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.