Evidence map›Paper›PMID 25478028›Full record

ArticleAlzheimer's research & therapy2014

Study protocol: Randomised controlled trial to evaluate the impact of an educational programme on Alzheimer's disease patients' quality of life.

Hélène Villars, Virginie Gardette, Amélie Perrin, Christophe Hein, Sophie Elmalem, Eva de Peretti, Audrey Zueras, Bruno Vellas, Fati Nourhashémi

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's research & therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01796314 (Impact of a Therapeutic Educational Programme for Alzheimer's Disease Patients and Their Caregiver in Community Dwelling, on the AD Patient's Quality of Life), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01796314 nacompletednot on this map

Impact of a Therapeutic Educational Programme for Alzheimer's Disease Patients and Their Caregiver in Community Dwelling, on the AD Patient's Quality of Life

TypeinterventionalSponsorUniversity Hospital, ToulouseRan2013 to 2017Enrolled170ConditionsAlzheimer DiseaseArmsTherapeutic Educational Program
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hélène VillarsGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France.
Virginie GardetteDepartment of Epidemiology and Public Health, Adresse 37, allées Jules Guesde, Toulouse Cedex, 31073, France ; Inserm U 1027, University Toulouse III, Toulouse, F-31073, France.
Amélie PerrinGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France.
Christophe HeinGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France.
Sophie ElmalemGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France.
Eva de PerettiGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France.
Audrey ZuerasGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France.
Bruno VellasGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France ; Inserm U 1027, University Toulouse III, Toulouse, F-31073, France.
Fati NourhashémiGeriatric Department, University Hospital, 170 avenue de Casselardit, Toulouse Cedex, 31059, France ; Inserm U 1027, University Toulouse III, Toulouse, F-31073, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTherapeutic education is expanding in the management of Alzheimer's disease (AD) patients. Several studies have revealed a positive impact of therapeutic educational programmes on the caregiver's burden and/or quality of life. However, to date, no study has evaluated its impact on the quality of life of the AD patient.

methodsThe THERAD study (THerapeutic Education in Alzheimer's Disease) is a 12-month randomised controlled trial that started in January 2013. This paper describes the study protocol. THERAD plans to enroll 170 dyads (AD patient and caregiver) on the basis of the following criteria: patient at a mild to moderately severe stage of AD, living at home, receiving support from a family caregiver. The main outcome is the patient's quality of life assessed by the Logsdon QoL-AD scale at 2 months, reported by the caregiver. The study is being led by geriatricians trained in therapeutic education at Toulouse University Hospital in France. To date, 107 caregiver/patient dyads have been recruited.

conclusionThis is the first trial designed to assess the specific impact of a therapeutic educational programme on the AD patient's quality of life. The final results will be available in 2015.

trial registration[ClinicalTrials.gov: NCT01796314] Registered 19 February 2013.

Identifiers

PMID25478028
PMCPMC4255540

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.