Evidence map›Paper›PMID 25477914›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2014

In vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkey.

Alicem Tekin, Tuba Dal, Özcan Deveci, Recep Tekin, Nida Özcan, Selahattin Atmaca, Saim Dayan

Open access · hybridAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Alicem TekinDepartment of Microbiology and Clinical Microbiology Medical Faculty Dicle University Diyarbakir Turkey Department of Microbiology and Clinical Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Tuba DalDepartment of Microbiology and Clinical Microbiology Medical Faculty Dicle University Diyarbakir Turkey Department of Microbiology and Clinical Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Özcan DeveciDepartment of Clinical Microbiology and Infectious Diseases Medical Faculty Dicle University Diyarbakir Turkey Department of Clinical Microbiology and Infectious Diseases, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Recep TekinDepartment of Clinical Microbiology and Infectious Diseases Medical Faculty Dicle University Diyarbakir Turkey Department of Clinical Microbiology and Infectious Diseases, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Nida ÖzcanDepartment of Microbiology and Clinical Microbiology Medical Faculty Dicle University Diyarbakir Turkey Department of Microbiology and Clinical Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Selahattin AtmacaDepartment of Microbiology and Clinical Microbiology Medical Faculty Dicle University Diyarbakir Turkey Department of Microbiology and Clinical Microbiology, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Saim DayanDepartment of Clinical Microbiology and Infectious Diseases Medical Faculty Dicle University Diyarbakir Turkey Department of Clinical Microbiology and Infectious Diseases, Medical Faculty, Dicle University, Diyarbakir, Turkey.
Dicle University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Staphylococcus species are one of the major causes of bacterial bloodstream infections. Multi-resistant staphylococci infections are major therapeutic problems. This study was aimed to detect methicillin, linezolid and vancomycin susceptibilities of Staphylococcus isolates. A total of 870 Staphylococcus strains isolated from blood cultures of hospitalized patients with BSI. Antimicrobial susceptibilities of methicillin, linezolid and vancomycin were detected according to the Clinical and Laboratory Standards Institute (CLSI). A total of 771 (88.6%) isolates were coagulase-negative staphylococci (CoNS). 700 (80.5%) isolates were methicillin-resistant (MR) and 170 (19.5%) were methicillin-susceptible (MS). All the MS isolates were also susceptible to linezolid. However 15 (1.7%) of MR strains were resistant to linezolid. The minimum inhibitory concentration range for the linezolid-resistant isolates by Etest was 6-32 μg/mL. The difference between linezolid susceptibilities for MS and MR staphylococci was not quite statistically significant (p = 0.052). There was no statistically significant difference between S. aureus and CoNS isolates for linezolid susceptibility. All of the isolates were susceptible to vancomycin. In conclusion, linezolid is currently an efficient option for the treatment of methicillin-resistant staphylococci infections.

Indexed as

AcetamidesAnti-Bacterial AgentsDrug Resistance, BacterialHumansLinezolidMethicillinMicrobial Sensitivity TestsOxazolidinonesSepsisStaphylococcal InfectionsStaphylococcus aureusTurkeyVancomycinAcetamidesAnti-Bacterial AgentsLinezolidMethicillinOxazolidinonesVancomycinlinezolidmethicillinStaphylococcusvancomycin

Identifiers

PMID25477914
PMCPMC4204965
OpenAlexW2106356587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.