Evidence map›Paper›PMID 25477894›Full record

ArticleFrontiers in plant science2014

An alternate route of ethylene receptor signaling.

Jingyi Zhang, Jing Yu, Chi-Kuang Wen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Uncertainty of EIN2Plant communications · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jingyi ZhangNational Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research (Shanghai), Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
Jing YuNational Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research (Shanghai), Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
Chi-Kuang WenNational Key Laboratory of Plant Molecular Genetics and National Center for Plant Gene Research (Shanghai), Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
Chinese Academy of Sciences · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gaseous plant hormone ethylene is perceived by a family of ethylene receptors and mediates an array of ethylene responses. In the absence of ethylene, receptor signaling is conveyed via the C-terminal histidine kinase domain to the N-terminus of the CONSTITUTIVE TRIPLE RESPONSE1 (CTR1) protein kinase, which represses ethylene signaling mediated by ETHYLENE INSENSITIVE2 (EIN2) followed by EIN3. In the presence of ethylene, the receptors are inactivated when ethylene binds to their N-terminal domain, and consequently CTR1 is inactive, allowing EIN2 and EIN3 to activate ethylene signaling. Recent findings have shown that the ethylene receptor N-terminal portion can conditionally mediate the receptor signal output in mutants lacking CTR1, thus providing evidence of an alternative pathway from the ethylene receptors not involving CTR1. Here we highlight the evidence for receptor signaling to an alternative pathway and suggest that receptor signaling is coordinated via the N- and C-termini, as we address the biological significance of the negative regulation of ethylene signaling by the two pathways.

Indexed as

ArabidopsisCTR1EIN2ethylene signalingETR1

Identifiers

PMID25477894
PMCPMC4238421
OpenAlexW2129754088

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.