ReviewFrontiers in immunology2014
Strategies to prevent preterm birth.
Review in Frontiers in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Is intimate partner violence and obstetrics characteristics of pregnant women associated with preterm birth in Ethiopia? Umbrella review on preterm birth.Reproductive health · 2023Pooled it
- Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.The Cochrane database of systematic reviews · 2020Pooled it
- The effect of pregnancy induced hypertension and multiple pregnancies on preterm birth in Ethiopia: a systematic review and meta-analysis.BMC research notes · 2019Pooled it
- Pooled it
- Specialist antenatal clinics for women at high risk of preterm birth: a systematic review of qualitative and quantitative research.BMC pregnancy and childbirth · 2017Pooled it
- Effect of a chimney-fitted improved stove on pregnancy outcomes in Northwest Ethiopia: a randomized controlled trial.BMC pregnancy and childbirth · 2024Trial
- The amniotic fluid cell-free transcriptome in spontaneous preterm labor.Scientific reports · 2021Trial
- Burden and predictors of bronchopulmonary dysplasia in preterm infants: A seven-year cohort.Journal of Taibah University Medical Sciences · 2026Article
- The probability of preterm or early term second live births in the southern U.S. State of Georgia, 2011-2020.BMC pregnancy and childbirth · 2025Article
- Data-driven machine learning algorithm model for pneumonia prediction and determinant factor stratification among children aged 6-23 months in Ethiopia.BMC infectious diseases · 2025Article
- Routine transabdominal cervical length screening in mid-pregnancy for the prevention of preterm birth: Is it good enough to use as a screening test?The Australian & New Zealand journal of obstetrics & gynaecology · 2025Article
- Applications of L-Arginine in Pregnancy and Beyond: An Emerging Pharmacogenomic Approach.Current gene therapy · 2025Review
- Association between parity and adverse maternal and neonatal outcomes: a population-based cross-sectional study.Frontiers in medicine · 2025Article
- Prevention Strategies and Management of Necrotizing Enterocolitis.Current treatment options in pediatrics · 2024Article
- Epidemiology, risk factors, clinical presentation and complications of late-onset neonatal sepsis among preterm neonates in Cyprus: a prospective case-control study.BMC pediatrics · 2024Article
- Article
- Should case management be considered a component of obstetrical interventions for pregnancies at risk of preterm birth?American journal of obstetrics and gynecology · 2023Review
- Article
- The role of vaginal progesterone in established pre-term labor: A randomized controlled trial.Journal of family medicine and primary care · 2022Article
- Understanding and Reducing Persistent Racial Disparities in Preterm Birth: a Model of Stress-Induced Developmental Plasticity.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After several decades of research, we now have evidence that at least six interventions are suitable for immediate use in contemporary clinical practice within high-resource settings and can be expected to safely reduce the rate of preterm birth. These interventions involve strategies to prevent non-medically indicated late preterm birth; use of maternal progesterone supplementation; surgical closure of the cervix with cerclage; prevention of exposure of pregnant women to cigarette smoke; judicious use of fertility treatments; and dedicated preterm birth prevention clinics. Quantification of the extent of success is difficult to predict and will be dependent on other clinical, cultural, societal, and economic factors operating in each environment. Further success can be anticipated in the coming years as other research discoveries are translated into clinical practice, including new approaches to treating intra-uterine infection, improvements in maternal nutrition, and lifestyle modifications to ameliorate maternal stress. The widespread use of human papillomavirus vaccination in girls and young women will decrease the need for surgical interventions on the cervix and can be expected to further reduce the risk of early birth. Together, this array of clinical interventions, each based on a substantial body of evidence, is likely to reduce rates of preterm birth and prevent death and disability in large numbers of children. The process begins with an acceptance that early birth is not an inevitable and natural feature of human reproduction. Preventative strategies are now available and need to be applied. The best outcomes may come from developing integrated strategies designed specifically for each health-care environment.
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