Evidence map›Paper›PMID 25477774›Full record

ArticleAdvanced functional materials2014

Stimuli-Responsive Materials for Controlled Release of Theranostic Agents.

Yucai Wang, Min Suk Shim, Nathanael S Levinson, Hsing-Wen Sung, Younan Xia

Abstract read
In one paragraph

Article in Advanced functional materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. COMolecules (Basel, Switzerland) · 2025
    Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Impact of Nanomedicine in Women's Metastatic Breast Cancer.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  14. Recent advances in the development of poly(ester amide)s-based carriers for drug delivery.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Review
  15. Review
  16. Cucurbit[8]uril-based supramolecular theranostics.Journal of nanobiotechnology · 2024
    Review
  17. Putting Hybrid Nanomaterials to Work for Biomedical Applications.Angewandte Chemie (International ed. in English) · 2024
    Review
  18. Responsive Supramolecular Polymers for Diagnosis and Treatment.International journal of molecular sciences · 2024
    Review
  19. Article
  20. Review

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yucai WangThe Wallace H. Coulter Department of Biomedical Engineering, School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Min Suk ShimDivision of Bioengineering, Incheon National University, Incheon, 406-772, Republic of Korea.
Nathanael S LevinsonThe Wallace H. Coulter Department of Biomedical Engineering, School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Hsing-Wen SungDepartment of Chemical Engineering and Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan, Republic of China.
Younan XiaThe Wallace H. Coulter Department of Biomedical Engineering, School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.

Funding

NIH Director's Pioneer AwardDP1OD000798 · OD · WASHINGTON UNIVERSITY · PI XIA, YOUNAN · 2006 to 2010
$3.8M
GOLD NANOCAGES AS A NEW CLASS OF THERAPEUTIC AGENTS FOR PHOTOTHERMAL CANCER TREATR01CA138527 · NCI · WASHINGTON UNIVERSITY · PI XIA, YOUNAN · 2010 to 2014
$1.9M
NCI NIH HHS R01 CA138527NIH HHS DP1 OD000798
6 · The paper itself

Abstract

Stimuli-responsive materials are so named because they can alter their physicochemical properties and/or structural conformations in response to specific stimuli. The stimuli can be internal, such as physiological or pathological variations in the target cells/tissues, or external, such as optical and ultrasound radiations. In recent years, these materials have gained increasing interest in biomedical applications due to their potential for spatially and temporally controlled release of theranostic agents in response to the specific stimuli. This article highlights several recent advances in the development of such materials, with a focus on their molecular designs and formulations. The future of stimuli-responsive materials will also be explored, including combination with molecular imaging probes and targeting moieties, which could enable simultaneous diagnosis and treatment of a specific disease, as well as multi-functionality and responsiveness to multiple stimuli, all important in overcoming intrinsic biological barriers and increasing clinical viability.

Indexed as

controlled releasesmart carriersstimuli-responsive materialstheranostics

Identifiers

PMID25477774
PMCPMC4249693

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.