ArticleJournal of food science and technology2014
Preparation of water-soluble melanin from squid ink using ultrasound-assisted degradation and its anti-oxidant activity.
Article in Journal of food science and technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Microbial production of eumelanin from a desert-derived Aspergillus terreus: statistical optimization, comprehensive characterization, and in silico insights into breast cancer-associated targets.Microbial cell factories · 2026Article
- Multifunctional Melanin Nanoparticles: Synthesis, Characterization, and Magnetic Resonance Imaging-Guided Biomedical Applications.Materials (Basel, Switzerland) · 2026Review
- Fabrication and Functional Modification Strategies of Squid Ink-Derived Nanoparticles: From Natural Melanin to Multifunctional Biomaterials.Marine drugs · 2026Review
- Water-soluble Cordyceps melanin: a photoprotector that enhances the survival of Beauveria bassiana and Metarhizium acridum conidia under UV-B radiation.World journal of microbiology & biotechnology · 2026Article
- Bioinspired nanoparticles prevent blue-light-induced skin hyperpigmentation via FZD2-TYR-melanin pathway.Materials today. Bio · 2025Article
- Article
- Influence of Cuttlefish-Ink Extract on Canned Golden Seabream (Foods (Basel, Switzerland) · 2024Article
- Melanin/melanin-like nanoparticles: As a naturally active platform for imaging-guided disease therapy.Materials today. Bio · 2023Review
- Exploring the Potential of Water-Soluble Squid Ink Melanin: Stability, Free Radical Scavenging, and CdFoods (Basel, Switzerland) · 2023Article
- The Enigmatic World of Fungal Melanin: A Comprehensive Review.Journal of fungi (Basel, Switzerland) · 2023Review
- Article
- Physicochemical properties, molecular structure, antioxidant activity, and biological function of extracellular melanin fromJournal of Zhejiang University. Science. B · 2022Article
- Natural Melanin: Current Trends, and Future Approaches, with Especial Reference to Microbial Source.Polymers · 2022Review
- Characterization of the physicochemical properties, antioxidant activity, and antiproliferative activity of natural melanin from S. reiliana.Scientific reports · 2022Article
- Sulfonated melanin derivatives: theoretical evaluation of local reactivities and chemical structures.Journal of molecular modeling · 2021Article
- Bioprocess of Microbial Melanin Production and Isolation.Frontiers in bioengineering and biotechnology · 2021Review
- Glucose Oxidase-Instructed Traceable Self-Oxygenation/Hyperthermia Dually Enhanced Cancer Starvation Therapy.Theranostics · 2020Article
- Reclamation of Fishery Processing Waste: A Mini-Review.Molecules (Basel, Switzerland) · 2019Article
- Squid Ink Polysaccharides Protect Human Fibroblast Against Oxidative Stress by Regulating NADPH Oxidase and Connexin43.Frontiers in pharmacology · 2019Article
- Effects of melanin from Sepiella Maindroni ink (MSMI) on the intestinal Microbiome of mice.BMC microbiology · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Water-soluble squid melanin fractions were firstly prepared using ultrasound-assistant degradation method under alkaline condition, which is optimized by response surface methodology. The processing melanin fractions were divided into different molecular weight (Mw) fractions by membrane separation (below 10 kDa, among 10-50 kDa and over 50 kDa). The AFM image and particle-size analysis showed monomer units of the melanin were destroyed, and huge polymers were degraded into smaller soluble particles after ultrasound. While, UV, IR and solid (13)C NMR spectra indicated that the basic structure of melanin fraction was still retained after ultrasound process. Further analysis showed soluble melanin fractions obtained in 0.5 and 1 M NaOH, with Mw above 10 kDa exhibited much higher in vitro antioxidant potency. The IC50 of these fractions (IC50 among 19-80 μg) on scavenging O 2 ∙¯ is more efficient than carnosine (IC50 = 355 μg/ml.), a commercialized antioxidant. They (IC50 mong 115-180 μg/ml) are as efficient as carnosine (IC50 = 110 μg/ml) on scavenging ∙OH. Our research has reported a novel method for preparation of water-soluble melanin fractions from squid ink, which could be a promising free radical scavenger from nature resource.
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