ArticleAJNR. American journal of neuroradiology2015
Susceptibility-weighted imaging in pediatric arterial ischemic stroke: a valuable alternative for the noninvasive evaluation of altered cerebral hemodynamics.
Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 32 citations in OpenAlex.
- Neonatal arterial ischemic stroke: an imaging overview.Pediatric radiology · 2026Review
- Correlation between asymmetrical vein sign of SWI and long-term clinical outcomes in patients with middle cerebral artery ischemic stroke.Japanese journal of radiology · 2024Article
- SWI and CTP fusion model based on sparse representation method to predict cerebral infarction trend.Frontiers in neuroscience · 2024Article
- Clinical Imaging of the Penumbra in Ischemic Stroke: From the Concept to the Era of Mechanical Thrombectomy.Frontiers in cardiovascular medicine · 2022Review
- Development of a photochemical thrombosis investigation system to obtain a rabbit ischemic stroke model.Scientific reports · 2021Article
- A Case of Cerebral Hyperperfusion Showing Unique Characteristics on Susceptibility-weighted MR Imaging after Carotid Endarterectomy.NMC case report journal · 2020Article
- Texture analysis of deep medullary veins on susceptibility-weighted imaging in infants: evaluating developmental and ischemic changes.European radiology · 2020Article
- Advanced multimodality neuroimaging of a giant, thrombosed MCA aneurysm complicated by an acute stroke in a pediatric patient.Radiology case reports · 2020Article
- Mapping the ischemic penumbra and predicting stroke progression in acute ischemic stroke: the overlooked role of susceptibility weighted imaging.Insights into imaging · 2020Article
- Susceptibility-weighted imaging in post-treatment evaluation in the early stage in patients with acute ischemic stroke.The Journal of international medical research · 2019Article
- Susceptibility-weighted imaging predicts infarct size and early-stage clinical prognosis in acute ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2018Article
- Increased susceptibility of asymmetrically prominent cortical veins correlates with misery perfusion in patients with occlusion of the middle cerebral artery.European radiology · 2017Article
- Susceptibility weighted imaging in acute cerebral ischemia: review of emerging technical concepts and clinical applications.The neuroradiology journal · 2017Review
- Susceptibility-Based Neuroimaging: Standard Methods, Clinical Applications, and Future Directions.Current radiology reports · 2017Article
- Removal of Arterial Vessel Contributions in Susceptibility-Weighted Images for Quantification of Normalized Visible Venous Volume in Children with Sickle Cell Disease.Journal of healthcare engineering · 2017Article
- Paediatric arterial ischemic stroke: acute management, recent advances and remaining issues.Italian journal of pediatrics · 2015Review
- Prominent vessel sign on susceptibility-weighted imaging in acute stroke: prediction of infarct growth and clinical outcome.PloS one · 2015Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeSWI provides information about blood oxygenation levels in intracranial vessels. Prior reports have shown that SWI focusing on venous drainage can provide noninvasive information about the degree of brain perfusion in pediatric arterial ischemic stroke. We aimed to evaluate the influence of the SWI venous signal pattern in predicting stroke evolution and the development of malignant edema in a large cohort of children with arterial ischemic stroke. MATERIALS AND
methodsA semiquantitative analysis of venous signal intensity on SWI and diffusion characteristics on DTI was performed in 16 vascular territories. The mismatch between areas with SWI-hypointense venous signal and restricted diffusion was correlated with stroke progression on follow-up. SWI-hyperintense signal was correlated with the development of malignant edema.
resultsWe included 24 children with a confirmed diagnosis of pediatric arterial ischemic stroke. Follow-up images were available for 14/24 children. MCA stroke progression on follow-up was observed in 5/6 children, with 2/8 children without mismatch between areas of initial SWI hypointense venous signal and areas of restricted diffusion on DTI. This mismatch showed a statistically significant association (P = .03) for infarct progression. Postischemic malignant edema developed in 2/10 children with and 0/14 children without SWI-hyperintense venous signal on initial SWI (P = .07).
conclusionsSWI-DTI mismatch predicts stroke progression in pediatric arterial ischemic stroke. SWI-hyperintense signal is not useful for predicting the development of malignant edema. SWI should be routinely added to the neuroimaging diagnostic protocol of pediatric arterial ischemic stroke.
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