ArticleEuropean radiology2015
Computed tomography, magnetic resonance imaging and FDG positron emission tomography in the management of vulvar malignancies.
Article in European radiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- PET Imaging in Vulvar Cancer: A Literature Review of the Current Evidence and Clinical Applications.Cancers · 2026Review
- Cancer of the vulva: 2025 update: FIGO Cancer Report 2025.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Imaging in Vulval Cancer.Cancers · 2024Review
- Review
- Management of Early-Stage Vulvar Cancer.Cancers · 2022Review
- Clinical and prognosticJapanese journal of radiology · 2022Article
- Cancer of the vulva: 2021 update.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021Article
- Diagnostic performance of preoperative [European journal of nuclear medicine and molecular imaging · 2021Article
- The role of PET/CT imaging in penile cancer.Translational andrology and urology · 2017Review
- 18F-FDG PET/CT in preoperative staging of vulvar cancer patients: is it really effective?Medicine · 2017Article
- The impact of FDG-PET/CT in the management of patients with vulvar and vaginal cancer.Gynecologic oncology · 2016Article
- State of the art in vulvar cancer imaging.Radiologia brasileiraArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo prospectively evaluate the value of CT or MRI (CT/MRI) and PET in the management of vulvar malignancies.
methodsAbdominal and pelvic CT/MRI and whole-body (18) F-FDG (fluorodeoxyglucose) PET or PET/CT (collectively designated PET hereafter) were performed. Lesion status was determined by the pathological findings or clinical follow-up. The diagnostic efficacy was evaluated by receiver operating characteristic (ROC) curve analysis. The clinical impact of PET was determined on a per scan basis.
resultsTwenty-three patients were enrolled, and 38 PET examinations were performed. CT/MRI and PET studies were used for primary staging (n = 17), monitoring the response (n = 7) and restaging after recurrence (n = 14). In primary staging, there was no significant difference between CT/MRI and PET in detecting metastatic inguinal lymph nodes (ILN). CT/MRI was significantly more efficacious than PET in detecting pelvic lymph node (PLN) or distant metastasis (p = 0.007 by ROC per patient basis). PET findings resulted in two positive impacts and one negative impact for both primary staging and restaging.
conclusionsFalse-positive PLN or distant metastasis PET findings are not uncommon, and hence should be interpreted with caution. PET can be supportive when metastatic ILN/PLN or distant metastasis is suspected on CT/MRI. KEY POINTS: • False-positive metastatic PLN or distant metastasis PET findings are not uncommon. • CT/MRI has value in the management of vulvar malignancies. • PET can be supportive when metastasis is suspected by CT/MRI.
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