Evidence map›Paper›PMID 25476705›Full record

ArticleChemical communications (Cambridge, England)2015

Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity.

Dawei Xu, Linhai Jiang, Anju Singh, Derek Dustin, Miao Yang, Ling Liu, Reidar Lund, Timothy J Sellati, He Dong

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Self-Assembling Peptide-Based Hydrogels for Wound Tissue Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
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  8. Article
  9. Article
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  11. Article
  12. Review
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  15. Article
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dawei XuDepartment of Chemistry & Biomolecular Science, Clarkson University, Potsdam, NY 13699, USA. hdong@clarkson.edu.
Linhai Jiang
Anju Singh
Derek Dustin
Miao Yang
Ling Liu
Reidar Lund
Timothy J Sellati
He Dong

Funding

Criteria-Directed Vaccine Generation Via Ag Mimicry, Adjuvancy, And APC-TargetingR01AI100138 · NIAID · ALBANY MEDICAL COLLEGE · PI GOSSELIN, EDMUND J, HAZLETT, KARSTEN R.O. · 2013 to 2017
$2.9M
NIAID NIH HHS AI100138NIAID NIH HHS R01 AI100138
6 · The paper itself

Abstract

This work demonstrates a design strategy to optimize antimicrobial peptides with an ideal balance of minimal cytotoxicity, enhanced stability, potent cell penetration and effective antimicrobial activity, which hold great promise for the treatment of intracellular microbial infections and potentially systemic anti-infective therapy.

Indexed as

Drug DesignNanostructuresAmino Acid SequenceAnimalsAnti-Bacterial AgentsBacteriaBone Marrow CellsCell SurvivalMiceModels, MolecularMonocytesPeptidesProtein ConformationAnti-Bacterial AgentsPeptides

Identifiers

PMID25476705
PMCPMC4866517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.