Evidence map›Paper›PMID 25476579›Full record

ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2015

Keeping an eye on SOXC proteins.

Lakshmi Pillai-Kastoori, Wen Wen, Ann C Morris

Abstract readReview
In one paragraph

Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Capn5 Expression in the Healthy and Regenerating Zebrafish Retina.Investigative ophthalmology & visual science · 2018
    Article
  5. Different Effect ofFrontiers in genetics · 2018
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lakshmi Pillai-Kastoori *Department of Biology, University of Kentucky, Lexington, Kentucky, USA.
Wen Wen *Department of Biology, University of Kentucky, Lexington, Kentucky, USA.
Ann C MorrisDepartment of Biology, University of Kentucky, Lexington, Kentucky, USA.

Funding

Vertebrate photoreceptor development and regenerationR01EY021769 · NEI · UNIVERSITY OF KENTUCKY · PI MORRIS, ANN C · 2012 to 2022
$3.2M
NEI NIH HHS R01 EY021769NEI NIH HHS R01EY021769
6 · The paper itself

Abstract

The formation of a mature, functional eye requires a complex series of cell proliferation, migration, induction among different germinal layers, and cell differentiation. These processes are regulated by extracellular cues such as the Wnt/BMP/Hh/Fgf signaling pathways, as well as cell intrinsic transcription factors that specify cell fate. In this review article, we provide an overview of stages of embryonic eye morphogenesis, extrinsic and intrinsic factors that are required for each stage, and pediatric ocular diseases that are associated with defective eye development. In addition, we focus on recent findings about the roles of the SOXC proteins in regulating vertebrate ocular development and implicating SOXC mutations in human ocular malformations.

Indexed as

AnimalsEyeEye ProteinsHumansOrganogenesisSOXC Transcription FactorsWnt Signaling PathwayEye ProteinsSOXC Transcription Factorseye developmentocular morphogenesisSOXC

Identifiers

PMID25476579
PMCPMC4344926

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.