Evidence map›Paper›PMID 25476541›Full record

ArticleInternational journal of legal medicine2015

Lung aeration on post-mortem magnetic resonance imaging is a useful marker of live birth versus stillbirth.

Joy L Barber, Neil J Sebire, Lyn S Chitty, Andrew M Taylor, Owen J Arthurs

Open access · hybridAbstract read
In one paragraph

Article in International journal of legal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Guideline
  2. Review
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  4. Review
  5. The current state of forensic imaging - post mortem imaging.International journal of legal medicine · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Forensic Aspects of Perinatal Deaths.Academic forensic pathology · 2018
    Review
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  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joy L BarberDepartment of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK, WC1N 3JH.
Neil J Sebire
Lyn S Chitty
Andrew M Taylor
Owen J Arthurs
Great Ormond Street Hospital for Children NHS Foundation Trust · GBUniversity College London · GB

Funding

Department of Health NIHR-CS-012-002Department of Health SRF/01/018
6 · The paper itself

Abstract

objectiveAim of this study was to investigate whether lung assessment on post-mortem magnetic resonance imaging (PMMR) can reliably differentiate between live birth and stillbirth. MATERIALS AND

methodsWe retrospectively assessed PMMR imaging features of a group of late foetal terminations following fetocide and stillbirths (without witnessed breathing) and early infant deaths (breathed spontaneously before death). PMMR images were reviewed for evidence of lung aeration and other features, blinded to the clinical and autopsy data.

resultsNineteen infant deaths (mean age 3.0 ± 6.5 post-natal weeks) and 23 foetal terminations or stillbirths (mean age 32.6 ± 10.2-week gestation) were compared. Subjective appearances of lung aeration on PMMR were the best indicator of live birth, with a sensitivity of 89.5% (95% confidence interval 68.6, 97.1%) and specificity of 95.6% (79.0, 99.2%) and positive and negative predictive values of 94.4% and 91.7%, respectively.

conclusionsLung aeration on PMMR appears to have high overall accuracy for confirmation of live birth versus intrauterine foetal death but now requires validating in a larger cohort of perinatal deaths.

Indexed as

AirImaging, Three-DimensionalPerinatal DeathPostmortem ChangesRespirationStillbirthAutopsyBiomarkersFemaleHumansInfant, NewbornLungMagnetic Resonance ImagingPregnancyRetrospective StudiesSensitivity and SpecificityBiomarkers

Identifiers

PMID25476541
PMCPMC4412725
OpenAlexW2156864319

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.