ArticleGenome biology2014
Discovery of genes affecting resistance of barley to adapted and non-adapted powdery mildew fungi.
Article in Genome biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
- Unlocking the genetic control of early seedling resistance to wheat powdery mildew through microphenomics.Pest management science · 2026Article
- Deep phenotyping platform for microscopic plant-pathogen interactions.Frontiers in plant science · 2025Article
- The improvement of the in vitro plant regeneration in barley with the epigenetic modifier of histone acetylation, trichostatin A.Journal of applied genetics · 2024Article
- Genetic Dissection of Spike Productivity Traits in the Siberian Collection of Spring Barley.Biomolecules · 2023Article
- Diversifying Resistance Mechanisms in Cereal Crops Using Microphenomics.Plant phenomics (Washington, D.C.) · 2023Review
- Barley guanine nucleotide exchange factor HvGEF14 is an activator of the susceptibility factor HvRACB and supports host cell entry by Blumeria graminis f. sp. hordei.Molecular plant pathology · 2022Article
- Specific Resistance of Barley to Powdery Mildew, Its Use and Beyond. A Concise Critical Review.Genes · 2020Review
- Article
- Genome-wide association mapping in a diverse spring barley collection reveals the presence of QTL hotspots and candidate genes for root and shoot architecture traits at seedling stage.BMC plant biology · 2019Article
- Reciprocal recurrent genomic selection: an attractive tool to leverage hybrid wheat breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Review
- siRNA-Finder (si-Fi) Software for RNAi-Target Design and Off-Target Prediction.Frontiers in plant science · 2019Article
- Article
- Gene coexpression network analysis combined with metabonomics reveals the resistance responses to powdery mildew in Tibetan hulless barley.Scientific reports · 2018Article
- Evolutionarily conserved partial gene duplication in the Triticeae tribe of grasses confers pathogen resistance.Genome biology · 2018Article
- Mapping resistance to powdery mildew in barley reveals a large-effect nonhost resistance QTL.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2018Article
- Barley susceptibility factor RACB modulates transcript levels of signalling protein genes in compatible interaction with Blumeria graminis f.sp. hordei.Molecular plant pathology · 2018Article
- Copy number variation and disease resistance in plants.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Review
- Altered Expression of Genes Implicated in Xylan Biosynthesis Affects Penetration Resistance against Powdery Mildew.Frontiers in plant science · 2017Article
- Coexpression network analysis of the genes regulated by two types of resistance responses to powdery mildew in wheat.Scientific reports · 2016Article
- An LRR/Malectin Receptor-Like Kinase Mediates Resistance to Non-adapted and Adapted Powdery Mildew Fungi in Barley and Wheat.Frontiers in plant science · 2016Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-host resistance, NHR, to non-adapted pathogens and quantitative host resistance, QR, confer durable protection to plants and are important for securing yield in a longer perspective. However, a more targeted exploitation of the trait usually possessing a complex mode of inheritance by many quantitative trait loci, QTLs, will require a better understanding of the most important genes and alleles.
resultsHere we present results from a transient-induced gene silencing, TIGS, approach of candidate genes for NHR and QR in barley against the powdery mildew fungus Blumeria graminis. Genes were selected based on transcript regulation, multigene-family membership or genetic map position. Out of 1,144 tested RNAi-target genes, 96 significantly affected resistance to the non-adapted wheat- or the compatible barley powdery mildew fungus, with an overlap of four genes. TIGS results for QR were combined with transcript regulation data, allele-trait associations, QTL co-localization and copy number variation resulting in a meta-dataset of 51 strong candidate genes with convergent evidence for a role in QR.
conclusionsThis study represents an initial, functional inventory of approximately 3% of the barley transcriptome for a role in NHR or QR against the powdery mildew pathogen. The discovered candidate genes support the idea that QR in this Triticeae host is primarily based on pathogen-associated molecular pattern-triggered immunity, which is compromised by effector molecules produced by the compatible pathogen. The overlap of four genes with significant TIGS effects both in the NHR and QR screens also indicates shared components for both forms of durable pathogen resistance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.