Evidence map›Paper›PMID 25475924›Full record

ArticleMycoses2014

Development of new strategies for early diagnosis of mucormycosis from bench to bedside.

Thomas J Walsh, Anna Skiada, Oliver A Cornely, Emmanuel Roilides, Ashraf Ibrahim, Theoklis Zaoutis, Andreas Groll, Olivier Lortholary, Dimitrios P Kontoyiannis, George Petrikkos

Open access · bronzeAbstract read
In one paragraph

Article in Mycoses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Mucormycosis in COVID-19 pandemic and its neurovascular spread.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Comparison of methods for isolating fungal DNA.Practical laboratory medicine · 2021
    Article
  15. Review
  16. Article
  17. Mucormycosis of the Central Nervous System.Journal of fungi (Basel, Switzerland) · 2019
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 4 countries.

Thomas J WalshHenry Schueler Foundation Scholar in Mucormycosis, Transplantation-Oncology Infectious Diseases Program, Infectious Diseases Translational Research Laboratory, Departments of Medicine, Pediatrics, and Microbiology and Immunology, Weill Cornell Medical Center of Cornell University, New York, NY, USA.
Anna Skiada
Oliver A Cornely
Emmanuel Roilides
Ashraf Ibrahim
Theoklis Zaoutis
Andreas Groll
Olivier Lortholary
Dimitrios P Kontoyiannis
George Petrikkos
Aristotle University of Thessaloniki · GRChildren's Hospital of Philadelphia · USCornell University · USHeidelberg University · DEInstitut Pasteur · FRNational and Kapodistrian University of Athens · GRThe Lundquist Institute · USThe University of Texas MD Anderson Cancer Center · USUniversity General Hospital Attikon · GRUniversity of Cologne · DE

Funding

Novel Toxins and Receptors in Mucormycosis Pathogenesis and TreatmentR01AI063503 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI IBRAHIM, ASHRAF S. · 2006 to 2025
$7.3M
NIAID NIH HHS R01 AI063503
6 · The paper itself

Abstract

Early diagnosis and initiation of amphotericin B (AmB) for treatment of mucormycosis increases survival from approximately 40% to 80%. The central objective of a new study of the European Confederation of Medical Mycology (ECMM) and the International Society for Human and Animal Mycology (ISHAM) Zygomycosis Working Group is to improve the clinical and laboratory diagnosis of mucormycosis. The diagnostic tools generated from this study may help to significantly improve survival from mucormycosis worldwide. The study has three major objectives: to conduct a prospective international registration of patients with mucormycosis using a well-established global network of centres; to construct a predictive risk model for patients at risk for mucormycosis; and to establish an international archive of specimens of tissues, fluids, and organisms linked from the patients enrolled into the registry that will be used for development of leading edge molecular, proteomic, metabolic and antigenic systems for mucormycosis.

Indexed as

Antifungal AgentsDatabases, FactualDiagnostic ImagingEarly DiagnosisHumansMicrobiological TechniquesMucoralesMucormycosisRegistriesRisk AssessmentSocieties, ScientificSpecimen HandlingAntifungal Agentsdiagnosisepidemiologymucormycosisnetworkzygomycosis

Identifiers

PMID25475924
PMCPMC4464811
OpenAlexW2114075419

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.