ArticlePloS one2014
Five-year incidence of primary open-angle glaucoma and rate of progression in health center-based Korean population: the Gangnam Eye Study.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Phenotypic and Genetic Links between Body Fat Measurements and Primary Open-Angle Glaucoma.International journal of molecular sciences · 2023Pooled it
- Alcohol, Intraocular Pressure, and Open-Angle Glaucoma: A Systematic Review and Meta-analysis.Ophthalmology · 2022Pooled it
- Obesity and risk of age-related eye diseases: a systematic review of prospective population-based studies.International journal of obesity (2005) · 2021Pooled it
- Epidemiology and risk factors of glaucoma in a comprehensive health screening baseline report from the Gangnam Eye Cohort Study.Scientific reports · 2025Article
- The potential role of adipokines and hepatokines in age-related ocular diseases.Metabolism open · 2025Review
- Low Body Mass Index Poses Greater Risk of Primary Open-Angle Glaucoma in African Ancestry Individuals.American journal of ophthalmology · 2025Article
- Obesity, body fat distribution and eye diseases.Eating and weight disorders : EWD · 2024Review
- Structure-function relationship in glaucoma: Optical coherence tomography en face imaging vs. red-free fundus photography.Eye (London, England) · 2023Article
- Differences in Factors Associated With Glaucoma Progression With Lower Normal Intraocular Pressure in Superior and Inferior Halves of the Optic Nerve Head.Translational vision science & technology · 2023Article
- Five-year incidence of primary glaucoma and related risk factors - The Handan eye study.Acta ophthalmologica · 2023Article
- Microbiome Dysbiosis: A Pathological Mechanism at the Intersection of Obesity and Glaucoma.International journal of molecular sciences · 2023Review
- U-Shaped Effect of Blood Pressure on Structural OCT Metrics and Retinal Perfusion in Ophthalmologically Healthy Subjects.Investigative ophthalmology & visual science · 2021Article
- Accuracy and reliability of measurements obtained with a noncontact tono-pachymeter for clinical use in mass screening.Scientific reports · 2021Article
- Review
- Ocular blood flow as a clinical observation: Value, limitations and data analysis.Progress in retinal and eye research · 2020Article
- Association between metabolic risk factors and optic disc cupping identified by deep learning method.PloS one · 2020Article
- Association between Platelet Parameters and Glaucoma Severity in Primary Open-Angle Glaucoma.Journal of ophthalmology · 2019Article
- Comparison of glaucoma patients referred by glaucoma screening versus referral from primary eye clinic.PloS one · 2019Article
- The Role of Diet in Glaucoma: A Review of the Current Evidence.Ophthalmology and therapy · 2018Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the 5-year incidence and progression rate of primary open-angle glaucoma (POAG) in a health-center-based Korean population.
methodsThe study population comprised 5,021 subjects who participated in standardized health screening (including non-contact tonometry and fundus photography) at the Gangnam Healthcare Center during the period from January 2005 to December 2006 and again from January 2010 to December 2011. Among these subjects, 948 (18.9%) with findings suggestive of glaucoma were subjected to a comprehensive glaucoma evaluation, which included applanation tonometry and standard automated perimetry. Based on the results, the subjects were diagnosed as POAG suspect or definite POAG.
resultsThe 5-year incidences of POAG suspect and definite POAG were 0.84% (42 subjects) and 0.72% (36 subjects), respectively. The rate of progression from POAG suspect to definite POAG was 4.75% per year. In subjects with a baseline intraocular pressure (IOP) >21 mmHg, the incidence of POAG suspect or definite POAG was significantly higher than in those with a baseline IOP ≤ 21 mmHg (32% vs. 1.05%; P<0.001). A multivariate analysis showed that the progression from POAG suspect to definite POAG was significantly associated with older age (odds ratio [OR], 1.07; 95% confidence interval [CI], 1.03-1.10), higher baseline IOP (OR, 1.10; 95% CI, 1.01-1.24), higher body mass index (BMI) (OR, 1.15; 95% CI, 1.03-1.31), higher education level (OR, 1.57; 95% CI, 1.05-2.17), and higher hematocrit level (OR, 1.22; 95% CI, 1.08-1.43).
conclusionsIn the health-center-based Korean population, the 5-year incidence of POAG was 0.72%, and the rate of progression from POAG suspect to definite POAG was 4.75% per year. This study identified old age, high baseline IOP, high BMI, high level of education, and high hematocrit level as significant risk factors for incident POAG.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.