Trial reportJAMA otolaryngology-- head & neck surgery2015
The use of clinical parameters to predict obstructive sleep apnea syndrome severity in children: the Childhood Adenotonsillectomy (CHAT) study randomized clinical trial.
Trial report in JAMA otolaryngology-- head & neck surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Study of Adenotonsillectomy for Children With Obstructive Sleep Apnea Syndrome
Is Change in Mouth Opening Related to Change in Quality of Life in Children With Type 1 Obstructive Sleep Apnea After Adenotonsillectomy? The JawChild Prospective Cohort Study
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 144 citations in OpenAlex.
- Sleep and pulmonary outcomes for clinical trials of airway plexiform neurofibromas in NF1.Neurology · 2016Guideline
- Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children.The Cochrane database of systematic reviews · 2015Pooled it
- Adenotonsillectomy vs Watchful Waiting in Pediatric Mild to Moderate Obstructive Sleep Apnea: The KATE Randomized Clinical Trial.JAMA otolaryngology-- head & neck surgery · 2025Trial
- Adenotonsillectomy for Snoring and Mild Sleep Apnea in Children: A Randomized Clinical Trial.JAMA · 2023Trial
- Cognitive parameters in children with mild obstructive sleep disordered breathing.Sleep & breathing = Schlaf & Atmung · 2021Trial
- Effectiveness of Adenotonsillectomy vs Watchful Waiting in Young Children With Mild to Moderate Obstructive Sleep Apnea: A Randomized Clinical Trial.JAMA otolaryngology-- head & neck surgery · 2020Trial
- The hypoxic burden algorithm: an integrated index for assessing intermittent hypoxia in pediatric obstructive sleep apnea-a retrospective cohort study.Translational pediatrics · 2026Article
- Risk Factors, Symptom Burden, and Treatment Response in Pediatric REM-Predominant OSA: Evidence From the Childhood Adenotonsillectomy Trial.Laryngoscope investigative otolaryngology · 2026Article
- Efficacy of van Beek headgear activator in adolescents with UARS and hyperdivergent skeletal class II malocclusion: dentofacial morphology, airway, and growth.BMC oral health · 2026Article
- Polysomnographic versus parent-reported predictors of executive function in children with sleep disordered breathing.International journal of pediatric otorhinolaryngology · 2026Article
- Article
- Preliminary Estimates of the Diagnostic Accuracy of Video Clips for Obstructive Sleep Apnea in Children.Pediatric pulmonology · 2025Article
- Assessment of Positional Obstructive Sleep Apnea in Children Undergoing Adenotonsillectomy for Obstructive Sleep Apnea.Laryngoscope investigative otolaryngology · 2025Article
- Obstructive sleep apnea risk and predictors among children in Boston and Lebanon.Journal of orthodontic science · 2025Article
- Gas exchange parameters for the prediction of obstructive sleep apnea in infants.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Allergic rhinitis as a predictor of moderate-to-severe paediatric obstructive sleep apnoea.Sleep & breathing = Schlaf & Atmung · 2024Article
- Associations between body mass index, sleep-disordered breathing, brain structure, and behavior in healthy children.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Effect of allergic rhinitis on sleep in children and the risk factors of an indoor environment.Sleep & breathing = Schlaf & Atmung · 2022Article
- Does sleep-disordered breathing add to impairments in academic performance and brain structure usually observed in children with overweight/obesity?European journal of pediatrics · 2022Article
- Use of facial stereophotogrammetry as a screening tool for pediatric obstructive sleep apnea by dental specialists.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 10 institutions in 1 country.
Funding
Abstract
importanceIt is important to distinguish children with different levels of severity of obstructive sleep apnea syndrome (OSAS) preoperatively using clinical parameters. This can identify children who most need polysomnography (PSG) prior to adenotonsillectomy (AT).
objectiveTo assess whether a combination of factors, including demographics, physical examination findings, and caregiver reports from questionnaires, can predict different levels of OSAS severity in children. DESIGN, SETTING, AND
participantsBaseline data from 453 children from the Childhood Adenotonsillectomy (CHAT) study were analyzed. Children 5.0 to 9.9 years of age with PSG-diagnosed OSAS, who were considered candidates for AT, were included.
interventionsPolysomnography for diagnosis of OSAS. MAIN OUTCOMES AND MEASURES: Linear or logistic regression models were fitted to identify which demographic, clinical, and caregiver reports were significantly associated with the apnea hypopnea index (AHI) and oxygen desaturation index (ODI).
resultsRace (African American), obesity (body mass index z score > 2), and the Pediatric Sleep Questionnaire (PSQ) total score were associated with higher levels of AHI and ODI (P = .05). A multivariable model that included the most significant variables explained less than 3% of the variance in OSAS severity as measured by PSG outcomes. Tonsillar size and Friedman palate position were not associated with increased AHI or ODI. Models that tested for potential effect modification by race or obesity showed no evidence of interactions with any clinical measure, AHI, or ODI (P > .20 for all comparisons). CONCLUSIONS AND RELEVANCE: This study of more than 450 children with OSAS identifies a number of clinical parameters that are associated with OSAS severity. However, information on demographics, physical findings, and questionnaire responses does not robustly discriminate different levels of OSAS severity.
trial registrationclinicaltrials.gov Identifier: NCT00560859.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.