Evidence map›Paper›PMID 25473441›Full record

ReviewInternational journal of stem cells2014

Concise Review: Differentiation of Human Adult Stem Cells Into Hepatocyte-like Cells In vitro.

Yunwei Zhang, Lijuan Xu, Shufang Wang, Changhao Cai, Li Yan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of stem cells, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yunwei ZhangDepartment of Gastroenterology, Institute of Geriatrics, Chinese PLA General Hospital, Beijing, China.
Lijuan XuDepartment of Gastroenterology, Institute of Geriatrics, Chinese PLA General Hospital, Beijing, China.
Shufang WangTransfusion Blood Department, Chinese PLA General Hospital, Beijing, China.
Changhao CaiDepartment of Gastroenterology, Institute of Geriatrics, Chinese PLA General Hospital, Beijing, China.
Li YanDepartment of Gastroenterology, Institute of Geriatrics, Chinese PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult stem cells (ASCs) are undifferentiated cells found throughout the body that divide to replenish dying cells and regenerate damaged tissues, which are the powerful sources for cell therapy and tissue engineering. Bone marrow-derived mesenchymal stem cells (BMSCs), adipose tissue-derived mesenchymal stem cells (ADSCs), and peripheral blood monocytes (PBMCs) are the common ASCs, and many studies indicated that ASCs isolated from various adult tissues could be induced to hepatocyte-like cells in vitro. However, the isolation, culture protocols, characterization of ASCs and hepatocyte-like cells are different. This review aims to describe the isolation and culture procedures for ASCs, to summarize the molecular characterization of ASCs, to characterize function of hepatocyte-like cells, and to discuss the future role of ASCs in cell therapy and tissue engineering.

Indexed as

Adipose tissue-derived mesenchymal stem cells Peripheral blood monocytesAdult stem cellsBone marrow-derived mesenchymal stem cellsHepatocyte-like cells

Identifiers

PMID25473441
PMCPMC4249903

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.