Evidence map›Paper›PMID 25473251›Full record

ArticleStatistica Sinica2012

Stochastic counterfactuals and stochastic sufficient causes.

Tyler J Vanderweele, James M Robins

Abstract read
In one paragraph

Article in Statistica Sinica, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A directed acyclic graph for interactions.International journal of epidemiology · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. A proof of Bell's inequality in quantum mechanics using causal interactions.Scandinavian journal of statistics, theory and applications · 2015
    Article
  14. Article
  15. Article
  16. Remarks on antagonism.American journal of epidemiology · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Tyler J VanderweeleDepartments of Epidemiology and Biostatistics, Harvard School of Public Health.
James M RobinsDepartments of Epidemiology and Biostatistics, Harvard School of Public Health.

Funding

Analytic Methods for HIV Treatment and Co-Factor EffectsR37AI032475 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ROBINS, JAMES M · 2005 to 2014
$6.0M
Theory and methods for sufficient cause interactionsR01ES017876 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI VANDERWEELE, TYLER · 2010 to 2014
$1.2M
NIAID NIH HHS R37 AI032475NIEHS NIH HHS R01 ES017876
6 · The paper itself

Abstract

Most work in causal inference concerns deterministic counterfactuals; the literature on stochastic counterfactuals is small. In the stochastic counterfactual setting, the outcome for each individual under each possible set of exposures follows a probability distribution so that for any given exposure combination, outcomes vary not only between individuals but also probabilistically for each particular individual. The deterministic sufficient cause framework supplements the deterministic counterfactual framework by allowing for the representation of counterfactual outcomes in terms of sufficient causes or causal mechanisms. In the deterministic sufficient cause framework it is possible to test for the joint presence of two causes in the same causal mechanism, referred to as a sufficient cause interaction. In this paper, these ideas are extended to the setting of stochastic counterfactuals and stochastic sufficient causes. Formal definitions are given for a stochastic sufficient cause framework. It is shown that the empirical conditions that suffice to conclude the presence of a sufficient cause interaction in the deterministic sufficient cause framework suffice also to conclude the presence of a sufficient cause interaction in the stochastic sufficient cause framework. Two examples from the genetics literature, in which there is evidence that sufficient cause interactions are present, are discussed in light of the results in this paper.

Indexed as

Causal inferenceInteractionStochastic counterfactualSufficient causeSynergism

Identifiers

PMID25473251
PMCPMC4249711

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.