Evidence map›Paper›PMID 25473209›Full record

ArticleJournal of Korean medical science2014

Effects of platelet-rich plasma, adipose-derived stem cells, and stromal vascular fraction on the survival of human transplanted adipose tissue.

Deok-Yeol Kim, Yi-Hwa Ji, Deok-Woo Kim, Eun-Sang Dhong, Eul-Sik Yoon

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Deok-Yeol KimDepartment of Plastic and Reconstructive Surgery, Korea University College of Medicine, Seoul, Korea.ORCID 0000-0001-6288-6597
Yi-Hwa JiMedical Science Research Center, Ansan Hospital, Korea University Medical Center, Ansan, Korea.ORCID 0000-0002-0556-2489
Deok-Woo KimDepartment of Plastic and Reconstructive Surgery, Korea University College of Medicine, Seoul, Korea.ORCID 0000-0003-2422-9662
Eun-Sang DhongDepartment of Plastic and Reconstructive Surgery, Korea University College of Medicine, Seoul, Korea.ORCID 0000-0002-5695-3914
Eul-Sik YoonDepartment of Plastic and Reconstructive Surgery, Korea University College of Medicine, Seoul, Korea.ORCID 0000-0001-5734-6625
Korea University · KRKorea University Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional adipose tissue transplantation has unpredictable viability and poor absorption rates. Recent studies have reported that treatment with platelet-rich plasma (PRP), adipose-derived stem cells (ASCs), and stromal vascular fraction (SVF) are related to increased survival of grafted adipose tissue. This study was the first simultaneous comparison of graft survival in combination with PRP, ASCs, and SVF. Adipose tissues were mixed with each other, injected subcutaneously into the back of nude mice, and evaluated at 4, 8, and 12 weeks. Human adipocytes were grossly maintained in the ASCs and SVF mixtures. Survival of the adipose tissues with PRP was observed at 4 weeks and with SVF at 8 and 12 weeks. At 12 weeks, volume reduction in the ASCs and SVF mixtures were 36.9% and 32.1%, respectively, which were significantly different from that of the control group without adjuvant treatment, 51.0%. Neovascular structures were rarely observed in any of the groups. Our results suggest that the technique of adding ASCs or SVF to transplanted adipose tissue might be more effective than the conventional grafting method. An autologous adipose tissue graft in combination with ASCs or SVF may potentially contribute to stabilization of engraftment.

Indexed as

Graft SurvivalPlatelet-Rich PlasmaAdipocytesAdipose TissueAdultAnimalsFemaleHumansMiceMice, Inbred BALB CMice, NudeStem CellsStromal CellsTransplantation, HeterologousAdipose TissuePlatelet-Rich PlasmaStem CellTissue Graft

Identifiers

PMID25473209
PMCPMC4248005
OpenAlexW2095702609

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.