Evidence map›Paper›PMID 25472889›Full record

SynthesisSchmerz (Berlin, Germany)2015

[Methodology of the development of the updated LONTS guidelines for long-term administration of opioids in noncancer pain].

W Häuser, P Klose, P Welsch, F Petzke, M Nothacker, I Kopp

Erratum issuedAbstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Schmerz (Berlin, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Mirtazapine for fibromyalgia in adults.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia.The Cochrane database of systematic reviews · 2018
    Pooled it
  3. Cannabinoids in Pain Management and Palliative Medicine.Deutsches Arzteblatt international · 2017
    Pooled it
  4. Antipsychotics for fibromyalgia in adults.The Cochrane database of systematic reviews · 2016
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Article
  9. Article
  10. Long-term opioid use in non-cancer pain.Deutsches Arzteblatt international · 2014
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

W HäuserMedizinisches Versorgungszentrum (Schmerztherapie, Palliativmedizin, Psychotherapie) Saarbrücken St. Johann, Saarbrücken, Deutschland, whaeuser@klinikum-saarbruecken.de.
P Klose
P Welsch
F Petzke
M Nothacker
I Kopp

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe update of the German S3 guidelines on long-term opioid therapy of chronic noncancer pain (CNCP), the"LONTS" (AWMF registration number 145/003) was scheduled for May 2014.

methodsThe guidelines were developed by 25 scientific societies and two patient self-help organizations under the coordination of the German Pain Society and the Association of the Scientific Medical Societies in Germany (AWMF).

resultsA systematic literature search was performed in the CENTRAL, MEDLINE and Scopus databases from October 2008 to October 2013. Meta-analyses of randomized controlled trials (RCT) of opioids in CNPC of study duration ≥ 4 weeks were conducted. Levels of evidence were assigned according to the Oxford Centre for Evidence-Based Medicine version 2009 classification system. The formulation and strength of recommendations was established in a multistep formalized consensus procedure, in accordance with AWFM rules and standards. The guidelines were reviewed by three scientific societies not involved in their development and were approved by the executive boards of the societies that were engaged in development of the guidelines.

conclusionThe guidelines will be published in several forms: complete and short scientific versions, as well as clinical practice and patient versions.

Indexed as

Long-Term CareAdolescentAdultAnalgesics, OpioidChildChronic PainConsensusEvidence-Based MedicineFemaleGermanyHumansInappropriate PrescribingInterdisciplinary CommunicationIntersectoral CollaborationMalePractice Guidelines as TopicAnalgesics, Opioid

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.