ArticleJournal of translational medicine2014
Synergy-COPD: a systems approach for understanding and managing chronic diseases.
Article in Journal of translational medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Molecular mechanisms underlying COPD-muscle dysfunction unveiled through a systems medicine approach.Bioinformatics (Oxford, England) · 2017Article
- Implementing systems medicine within healthcare.Genome medicine · 2015Article
- The COPD Knowledge Base: enabling data analysis and computational simulation in translational COPD research.Journal of translational medicine · 2014Article
- Biomedical research in a Digital Health Framework.Journal of translational medicine · 2014Article
- Systems Medicine: from molecular features and models to the clinic in COPD.Journal of translational medicine · 2014Article
- Chronic Obstructive Pulmonary Disease heterogeneity: challenges for health risk assessment, stratification and management.Journal of translational medicine · 2014Review
- Predictive medicine: outcomes, challenges and opportunities in the Synergy-COPD project.Journal of translational medicine · 2014Review
- Computational modeling of the obstructive lung diseases asthma and COPD.Journal of translational medicine · 2014Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic diseases (CD) are generating a dramatic societal burden worldwide that is expected to persist over the next decades. The challenges posed by the epidemics of CD have triggered a novel health paradigm with major consequences on the traditional concept of disease and with a profound impact on key aspects of healthcare systems. We hypothesized that the development of a systems approach to understand CD together with the generation of an ecosystem to transfer the acquired knowledge into the novel healthcare scenario may contribute to a cost-effective enhancement of health outcomes. To this end, we designed the Synergy-COPD project wherein the heterogeneity of chronic obstructive pulmonary disease (COPD) was addressed as a use case representative of CD. The current manuscript describes main features of the project design and the strategies put in place for its development, as well the expected outcomes during the project life-span. Moreover, the manuscript serves as introductory and unifying chapter of the different papers associated to the Supplement describing the characteristics, tools and the objectives of Synergy-COPD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.