ArticleSurgical endoscopy2015
Endoscopic mucosal resection for staging and treatment of early esophageal carcinoma: a single institution experience.
Article in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Predicting the magnitude of risk for non-curative endoscopic submucosal dissection in superficial esophageal cancer using explainable artificial intelligence.World journal of gastrointestinal oncology · 2026Article
- Esophageal mucosal auto-transplantation versus acellular dermal matrix transplantation for preventing esophageal stenosis after endoscopic resection in patients with superficial esophageal mucosal lesions.Surgical endoscopy · 2025Article
- Combined treatment of refractory benign stricture after esophageal endoscopic mucosal dissection: A case report.World journal of clinical cases · 2023Article
- Geographic distribution of colonoscopy providers in the United States: An analysis of medicare claims data.Surgical endoscopy · 2022Article
- Variation in Diagnosis, Treatment, and Outcome of Esophageal Cancer in a Regionalized Care System in Ontario, Canada.JAMA network open · 2021Article
- Evolution in the Treatment of Esophageal Disease at a Single Academic Institution: 2004-2013.Journal of laparoendoscopic & advanced surgical techniques. Part A · 2017Article
- Advances in the Diagnosis and Treatment of Barrett's Esophagus and Early Esophageal Cancer; Summary of the Kelly and Carlos Pellegrini SSAT/SAGES Luncheon Symposium.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017Review
- Surgical Treatment of High-Grade Dysplasia and Early Esophageal Cancer.World journal of surgery · 2017Review
- Minimally invasive staging of esophageal cancer.Annals of cardiothoracic surgery · 2017Review
- Performance measures for upper gastrointestinal endoscopy: A European Society of Gastrointestinal Endoscopy quality improvement initiative.United European gastroenterology journal · 2016Review
- Epidemiology, Diagnosis, and Management of Esophageal Adenocarcinoma.Gastroenterology · 2015Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic mucosal resection (EMR) has emerged for evaluation and treatment of esophageal nodules. We report our initial experience with EMR for T staging and management of early esophageal cancer.
methodsWe reviewed patients undergoing EMR for esophageal adenocarcinoma between 2008 and 2013. The primary outcome measure was needed for esophagectomy. Secondary outcomes included complete eradication of adenocarcinoma, recurrence or persistence of cancer, nodal status for those undergoing esophagectomy, and complications of endoscopic treatment.
resultsDuring the study period, 24 patients underwent EMR demonstrating carcinoma, and a grossly margin negative endoscopic resection was achieved in all cases. Ten patients (42 %) had evidence of submucosal invasion and were referred for esophagectomy. Patients with margin negative EMR (n = 10, 42 %) or positive radial margins (n = 4, 16 %) underwent endoscopic surveillance and treatment with radiofrequency ablation or repeat EMR as needed. Thirteen patients (93 %) with intramucosal cancer (IMC) have been successfully managed with ongoing endoscopic surveillance and treatment with a median follow-up of 15.5 months. One patient underwent esophagectomy due to recurrent IMC in the setting of long-segment multifocal high-grade dysplasia. There were no esophageal perforations, one patient developed a self-limited gastrointestinal hemorrhage following EMR, and one had an esophageal stricture following endoscopic management.
conclusionsIMC can be successfully managed endoscopically and thus esophagectomy is avoided in a significant proportion of patients. Endoscopic management may be utilized in the setting of complete resection or radial margin involvement without evidence of submucosal invasion. Close endoscopic follow-up is of paramount importance even in those with negative margins, because recurrent disease may occur following EMR in these patients.
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