ArticleEnvironmental science and pollution research international2015
Non-avoidance behaviour in enchytraeids to boric acid is related to the GABAergic mechanism.
Article in Environmental science and pollution research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 44 citations in OpenAlex.
- Safer and Sustainable-by-Design Hydroxyapatite Nanobiomaterials for Biomedical Applications: Assessment of Environmental Hazards.Nanomaterials (Basel, Switzerland) · 2022Article
- Single and Mixture Toxicity of Boron and Vanadium Nanoparticles in the Soil AnnelidNanomaterials (Basel, Switzerland) · 2022Article
- Environmental Hazards of Boron and Vanadium Nanoparticles in the Terrestrial Ecosystem-A Case Study withNanomaterials (Basel, Switzerland) · 2021Article
- Effects of Amorphous Silica Nanopowders on the Avoidance Behavior of Five Soil Species-A Screening Study.Nanomaterials (Basel, Switzerland) · 2020Article
- Review
- Effectiveness of Boric Acid by Ingestion, But Not by Contact, Against the Common Bed Bug (Hemiptera: Cimicidae).Journal of economic entomology · 2018Article
- Boric acid as reference substance for ecotoxicity tests in tropical artificial soil.Ecotoxicology (London, England) · 2018Article
- Ecotoxicity of boric acid in standard laboratory tests with plants and soil organisms.Ecotoxicology (London, England) · 2017Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Soil invertebrates, e.g. enchytraeids, are known to be able to avoid unfavourable conditions, which gives them an important ecological advantage. These organisms possess chemoreceptors that can detect stressors, which in turn activate responses such as avoidance behaviour. We studied the avoidance behaviour in response to boric acid (BA) using enchytraeids. Results showed not only no avoidance, but that increasing concentrations seemed to have an "attraction" effect. To study the underlying mechanism, a selection of genes targeting for neurotransmission pathways (acetylcholinesterase (AChE) and gamma-aminobutyric acid receptor (GABAr)) were quantified via quantitative real-time polymerase chain reaction (qPCR). Evidences were that BA is neurotoxic via the GABAergic system mechanism where it acts as a GABA-associated protein receptor (GABAAR) antagonist possibly causing anaesthetic effects. This is the first time that (non)avoidance behaviour in invertebrates was studied in relation with the GABAergic system. We strongly recommend the combination of such gene and/or functional assay studies with the avoidance behaviour test as it can bring many advantages and important interpretation lines for ecotoxicity with minor effort.
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