ArticleJournal of translational medicine2014
Simulation environment and graphical visualization environment: a COPD use-case.
Article in Journal of translational medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- Systems Medicine: from molecular features and models to the clinic in COPD.Journal of translational medicine · 2014Article
- The COPD Knowledge Base: enabling data analysis and computational simulation in translational COPD research.Journal of translational medicine · 2014Article
- Clinical Decision Support Systems (CDSS) for preventive management of COPD patients.Journal of translational medicine · 2014Article
- Biomedical research in a Digital Health Framework.Journal of translational medicine · 2014Article
- Predictive medicine: outcomes, challenges and opportunities in the Synergy-COPD project.Journal of translational medicine · 2014Review
- Synergy-COPD: a systems approach for understanding and managing chronic diseases.Journal of translational medicine · 2014Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundToday, many different tools are developed to execute and visualize physiological models that represent the human physiology. Most of these tools run models written in very specific programming languages which in turn simplify the communication among models. Nevertheless, not all of these tools are able to run models written in different programming languages. In addition, interoperability between such models remains an unresolved issue.
resultsIn this paper we present a simulation environment that allows, first, the execution of models developed in different programming languages and second the communication of parameters to interconnect these models. This simulation environment, developed within the Synergy-COPD project, aims at helping and supporting bio-researchers and medical students understand the internal mechanisms of the human body through the use of physiological models. This tool is composed of a graphical visualization environment, which is a web interface through which the user can interact with the models, and a simulation workflow management system composed of a control module and a data warehouse manager. The control module monitors the correct functioning of the whole system. The data warehouse manager is responsible for managing the stored information and supporting its flow among the different modules.
conclusionIt has been proved that the simulation environment presented here allows the user to research and study the internal mechanisms of the human physiology by the use of models via a graphical visualization environment. A new tool for bio-researchers is ready for deployment in various use cases scenarios.
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