Evidence map›Paper›PMID 25471294›Full record

ArticleBMC infectious diseases2014

Protective effect of exclusive breastfeeding against hand, foot and mouth disease.

Hualiang Lin, Limei Sun, Jinyan Lin, Jianfeng He, Aiping Deng, Min Kang, Hanri Zeng, Wenjun Ma, Yonghui Zhang

Abstract read
In one paragraph

Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Current status of hand-foot-and-mouth disease.Journal of biomedical science · 2023
    Review
  7. Exclusive Breastfeeding and Childhood Morbidity: A Narrative Review.International journal of environmental research and public health · 2022
    Review
  8. Article
  9. Hand, Foot, and Mouth Disease: A Narrative Review.Recent advances in inflammation & allergy drug discovery · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Hand-Washing: The Main Strategy for Avoiding Hand, Foot and Mouth Disease.International journal of environmental research and public health · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hualiang LinGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, 511430, China. linhualiang2002@163.com.
Limei SunGuangdong Provincial Center for Disease Control and Prevention, 160, Qunxian Road, Panyu, Guangzhou, 511430, China. cdcslm@126.com.
Jinyan LinGuangdong Provincial Center for Disease Control and Prevention, 160, Qunxian Road, Panyu, Guangzhou, 511430, China. linjy1957@sohu.com.
Jianfeng HeGuangdong Provincial Center for Disease Control and Prevention, 160, Qunxian Road, Panyu, Guangzhou, 511430, China. hjf@cdcp.org.cn.
Aiping DengGuangdong Provincial Center for Disease Control and Prevention, 160, Qunxian Road, Panyu, Guangzhou, 511430, China. dapgdeis@vip.sina.com.
Min KangGuangdong Provincial Center for Disease Control and Prevention, 160, Qunxian Road, Panyu, Guangzhou, 511430, China. kangmin@cdcp.org.cn.
Hanri ZengGuangdong Provincial Center for Disease Control and Prevention, 160, Qunxian Road, Panyu, Guangzhou, 511430, China. zyh@cdcp.org.cn.
Wenjun MaGuangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, 511430, China. mawj@gdiph.gov.cn.
Yonghui ZhangGuangdong Provincial Center for Disease Control and Prevention, 160, Qunxian Road, Panyu, Guangzhou, 511430, China. zyh@cdcp.org.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfants who are exclusively breastfed receive natural protection against some infectious agents. This study examined whether there was protective effect of exclusive breastfeeding on the occurrence of hand, foot and mouth disease, which was an emerging infectious disease among children in China.

methodsA community-based case-control study was carried out among children age 4 years or younger in Guangdong Province, China. Cases were newly diagnosed hand, foot and mouth disease. Controls were randomly sampled from healthy children from the nearby village. Unconditional logistic regression model was used to estimate the odds ratio (OR) for exclusive breastfeeding after adjusting for potential confounding factors.

resultsA total of 316 cases and 566 controls were included in the analysis. Significantly beneficial effect of exclusive breastfeeding during the first 6 months was observed for hand, foot and mouth disease occurrence. The overall OR was 0.63 (95% CI: 0.47-0.85) for exclusive breastfeeding compared with mixed feeding type. The age-specific analyses indicated that the protective effect persisted till the age of 28 months.

conclusionsThis study suggests that exclusive breastfeeding might have protective effect against HFMD infection among the children within 28 months of age.

Indexed as

Breast FeedingAge FactorsCase-Control StudiesChild, PreschoolChinaCommunicable Diseases, EmergingCommunity Health ServicesConfidence IntervalsFemaleHand, Foot and Mouth DiseaseHumansInfantInterviews as TopicMaleOdds RatioRisk Factors

Identifiers

PMID25471294
PMCPMC4273484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.