Trial reportEuropean journal of applied physiology2015
Impact of acute sodium citrate ingestion on endurance running performance in a warm environment.
Trial report in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Pooled it
- Extracellular Buffering Supplements to Improve Exercise Capacity and Performance: A Comprehensive Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Impact of sodium citrate ingestion during recovery after strenuous exercise in the heat on heart rate variability: A randomized, crossover study.Physiological reports · 2022Trial
- Does varying the ingestion period of sodium citrate influence blood alkalosis and gastrointestinal symptoms?PloS one · 2021Trial
- Sodium citrate ingestion protocol impacts induced alkalosis, gastrointestinal symptoms, and palatability.Physiological reports · 2019Trial
- Use of Buffers in Specific Contexts: Highly Trained Female Athletes, Extreme Environments and Combined Buffering Agents-A Narrative Review.Sports medicine (Auckland, N.Z.) · 2023Review
- Time to Optimize Supplementation: Modifying Factors Influencing the Individual Responses to Extracellular Buffering Agents.Frontiers in nutrition · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDietary supplements inducing alkalosis have been shown to be ergogenic during intense endurance exercise in temperate environments, but there is lack of data regarding the efficacy of these substances in the heat. This study aimed to investigate the effect of sodium citrate (CIT) ingestion on 5,000-m running performance in a warm environment.
methodsSixteen non-heat-acclimated endurance-trained males (age 25.8 ± 4.4 years, VO2peak 56.9 ± 4.7 mL kg min) completed two 5,000-m self-paced treadmill runs with preceding CIT or placebo (wheat flour; PLC) ingestion in a double-blind, randomized, crossover manner in a climatic chamber (air temperature 32 °C, relative humidity 50 %).
resultsCIT ingestion (500 mg kg(-1) body mass) compared to PLC induced increases in water retention, body mass and plasma volume (P < 0.05). Pre- and post-exercise blood HCO3 (-) concentration, base excess and pH were higher (P < 0.001) in CIT compared to PLC trial. Rectal temperature, body heat storage, heat storage rate, heart rate and 5,000-m running time (18.92 ± 2.05 min in CIT, 19.11 ± 2.38 min in PLC; 66 % likelihood of benefit, d = -0.09) were similar (P > 0.05) in the two trials. Post-exercise blood lactate concentration was higher (P < 0.001) in CIT (11.05 ± 3.22 mmol L(-1)) compared to PLC trial (8.22 ± 2.64 mmol L(-1)). Ratings of perceived exertion, fatigue and thermal sensation did not differ in the two trials (P > 0.05).
conclusionAcute CIT ingestion induces alkalosis, water retention, plasma volume expansion and an increase in post-exercise blood lactate concentration, but does not improve 5,000-m running performance in a warm environment in non-heat-acclimated endurance-trained males.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.