ArticleNaunyn-Schmiedeberg's archives of pharmacology2015
Report on the Third Symposium "cCMP and cUMP as New Second Messengers".
Article in Naunyn-Schmiedeberg's archives of pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Bacterial Nucleotidyl Cyclase Inhibits the Host Innate Immune Response by Suppressing TAK1 Activation.Infection and immunity · 2017Article
- Naunyn-Schmiedeberg's Archives of Pharmacology under new editorship: change and continuity.Naunyn-Schmiedeberg's archives of pharmacology · 2016Article
- Heterogeneity of pulmonary endothelial cyclic nucleotide response to Pseudomonas aeruginosa ExoY infection.American journal of physiology. Lung cellular and molecular physiology · 2015Article
- Cross Kingdom Activators of Five Classes of Bacterial Effectors.PLoS pathogens · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cyclic pyrimidine nucleotides cytidine 3',5'-cyclic monophosphate (cCMP) and uridine 3',5'-cyclic monophosphate (cUMP) have been unequivocally identified in mammalian cells using the most advanced mass spectrometry methods. On October 10, 2014, leading experts in the field met at the Hannover Medical School, Hannover, Germany, to discuss the latest findings in this emerging field of research. Generators, effectors, biological functions, inactivation mechanisms, and model systems for cCMP and cUMP were discussed. Pseudomonas aeruginosa nucleotidyl cyclase toxin ExoY, effectively producing cUMP, was a central topic of the meeting. cCMP and cUMP fulfill the criteria for second messengers. Future research directions in the field will include the identification of specific effector proteins of cCMP and cUMP, new cCMP- and cUMP-generating bacterial toxins, the analysis of new model organisms such as the zebra fish, and elucidation of the function of other noncanonical cyclic nucleotides such as inosine 3',5'-cyclic monophosphate (cIMP).
Indexed as
Identifiers
25471064What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.