Evidence map›Paper›PMID 25470776›Full record

Observational studyPloS one2014

Renal water molecular diffusion characteristics in healthy native kidneys: assessment with diffusion tensor MR imaging.

Zhenfeng Zheng, Huilan Shi, Jing Zhang, Yunting Zhang

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  4. Article
  5. Diffusion tensor imaging of the healthy feline kidney.Journal of feline medicine and surgery · 2026
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  13. World journal of radiology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhenfeng ZhengDepartment of Nephrology, General Hospital of Tianjin Medical University, Heping District, Tianjin, China.
Huilan ShiDepartment of Radiology, General Hospital of Tianjin Medical University, Heping District, Tianjin, China.
Jing ZhangDepartment of Radiology, General Hospital of Tianjin Medical University, Heping District, Tianjin, China.
Yunting ZhangDepartment of Radiology, General Hospital of Tianjin Medical University, Heping District, Tianjin, China.
Tianjin Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo explore the characteristics of diffusion tensor imaging (DTI) and magnetic resonance (MR) imaging in healthy native kidneys.

methodsSeventy-three patients without chronic kidney disease underwent DTI-MRI with spin echo-echo planar (SE-EPI) sequences accompanied by an array spatial sensitivity encoding technique (ASSET). Cortical and medullary mean, axial and radial diffusivity (MD, AD and RD), fractional anisotropy (FA) and primary, secondary and tertiary eigenvalues (λ1, λ2, λ3) were analysed in both kidneys and in different genders.

resultsCortical MD, λ2, λ3, and RD values were higher than corresponding medullary values. The cortical FA value was lower than the medullary FA value. Medullary λ1 and RD values in the left kidney were lower than in the right kidney. Medullary λ2, and λ3 values in women were higher than those in men. Medullary FA values in women were lower than those in men. Medullary FA (r = 0.351, P = 0.002) and λ1 (r = 0.277, P = 0.018) positively correlated with eGFR. Medullary FA (r = -0.25, P = 0.033) negatively correlated with age.

conclusionsRenal water molecular diffusion differences exist in human kidneys and genders. Age and eGFR correlate with medullary FA and primary eigenvalue.

Indexed as

AdultAgedDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingFemaleGlomerular Filtration RateHealthy VolunteersHumansKidneyMaleMiddle AgedPilot ProjectsWaterWater

Identifiers

PMID25470776
PMCPMC4254455
OpenAlexW2056968778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.