Evidence map›Paper›PMID 25470566›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2015

NMR hyperpolarization techniques for biomedicine.

Panayiotis Nikolaou, Boyd M Goodson, Eduard Y Chekmenev

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers.

0numbers the graph read from it
0cells of the map it votes in
160citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

160 citing papers in PubMed.

  1. Article
  2. Multidimensional pH-Temperature Mapping of SABRE-SHEATHThe journal of physical chemistry. B · 2025
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  3. The journal of physical chemistry. B · 2025
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  4. The journal of physical chemistry. B · 2025
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  5. Article
  6. EfficientJournal of magnetic resonance open · 2025
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  7. SABRE-SHEATH hyperpolarizedChemical communications (Cambridge, England) · 2025
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  8. Parahydrogen-Hyperpolarized Propane-The journal of physical chemistry. A · 2025
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  9. Science advances · 2025
    Article
  10. Article
  11. The journal of physical chemistry. B · 2025
    Article
  12. High HThe journal of physical chemistry letters · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Toward Ultra-High-Quality-Factor Wireless Masing Magnetic Resonance Sensing.Angewandte Chemie (International ed. in English) · 2024
    Article
  20. Article

100 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Panayiotis NikolaouInstitute of Imaging Science (VUIIS), Department of Radiology, Department of Biomedical Engineering, Department of Physics and Astronomy and Department of Biochemistry, Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University, 1161 21st Ave South AA-1107, Nashville, Tennessee, 37232-2310 (USA).
Boyd M Goodson
Eduard Y Chekmenev

Funding

Pure parahydrogen-enhanced metabolic MRI contrast agents for molecular imagingR21EB018014 · NIBIB · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI CHEKMENEV, EDUARD, GOODSON, BOYD M · 2014 to 2015
$407k
NIBIB NIH HHS 1R21EB018014NIBIB NIH HHS R21 EB018014
6 · The paper itself

Abstract

Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo molecular imaging modalities, ranging from functional imaging of the lungs to metabolic imaging of cancer. This Concept article explores selected advances in methods for the preparation and use of hyperpolarized contrast agents, many of which are already at or near the phase of their clinical validation in patients.

Indexed as

Contrast MediaHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyContrast Mediadynamic nuclear polarizationhyperpolarizationmedicinal chemistrymolecular imagingspin exchange optical pumping

Identifiers

PMID25470566
PMCPMC4418426

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.