ArticleNature2015
Native structure of photosystem II at 1.95 Å resolution viewed by femtosecond X-ray pulses.
Article in Nature, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 332 papers.
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Who cites it
332 citing papers in PubMed, 1,172 citations in OpenAlex.
- Photosystem I structural fusion with IsiA enhances light-harvesting capabilities of filamentous cyanobacterium during iron deficiency.Cell reports. Physical science · 2026Article
- POM-Based Water Splitting Catalyst Under Acid Conditions Driven by Its Assembly on Carbon Nanotubes.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- New Water Oxidation Mechanism in Photosystem II Resolves Major Experimental Controversies.Angewandte Chemie (International ed. in English) · 2026Article
- An additional water is introduced into the manganese cluster during the formation of the SNature communications · 2026Article
- Asymmetric Connectivity Between Redox-Active Tyrosines and Reaction-Center Chlorophylls in Photosystem II.Plants (Basel, Switzerland) · 2026Article
- Photosystem-Based Biophotoelectrodes for Solar Energy Conversion.Chemical reviews · 2026Article
- The contribution of thePhotosynthesis research · 2026Article
- Comment on Photosystem II: light-dependent oscillation of ligand composition at its active site: existence of O6 in SActa crystallographica. Section D, Structural biology · 2026Article
- The structure of intact and active Photosystem II from Arabidopsis thaliana at 2.44 Å resolution.The New phytologist · 2026Article
- From manganese mineral evolution history to atmospheric oxygen reconstruction.National science review · 2026Article
- Generation and modulation of catalytically relevant states of a dye-decolourizing peroxidase using time-resolved serial femtosecond crystallography with drop-on-chip mixing and X-ray-driven reduction.Acta crystallographica. Section D, Structural biology · 2026Article
- Article
- Living Photoanodes for Solar-Driven Water Oxidation.Chemical reviews · 2026Review
- Simultaneous lasing of Ni Kα and Cu Kα lasers from an alloy foil irradiated with an intense X-ray free-electron laser pulse.Journal of synchrotron radiation · 2026Article
- Revealing Missing Links in the Downsizing of the Photosystem II Antenna in Higher Plants Under Stress Conditions.Antioxidants (Basel, Switzerland) · 2025Article
- Photosystem II: commonality and diversity with emphasis on the extrinsic subunits.Plant & cell physiology · 2025Review
- Current perspectives on proton and electron transfer pathways in photosystem II water oxidation.Plant & cell physiology · 2025Review
- Electronic Structure of the SACS physical chemistry Au · 2025Article
- Review
- The Photosynthetic Complexes of Thylakoid Membranes of Photoautotrophs and a Quartet of Their Polar Lipids.International journal of molecular sciences · 2025Review
272 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photosynthesis converts light energy into biologically useful chemical energy vital to life on Earth. The initial reaction of photosynthesis takes place in photosystem II (PSII), a 700-kilodalton homodimeric membrane protein complex that catalyses photo-oxidation of water into dioxygen through an S-state cycle of the oxygen evolving complex (OEC). The structure of PSII has been solved by X-ray diffraction (XRD) at 1.9 ångström resolution, which revealed that the OEC is a Mn4CaO5-cluster coordinated by a well defined protein environment. However, extended X-ray absorption fine structure (EXAFS) studies showed that the manganese cations in the OEC are easily reduced by X-ray irradiation, and slight differences were found in the Mn-Mn distances determined by XRD, EXAFS and theoretical studies. Here we report a 'radiation-damage-free' structure of PSII from Thermosynechococcus vulcanus in the S1 state at a resolution of 1.95 ångströms using femtosecond X-ray pulses of the SPring-8 ångström compact free-electron laser (SACLA) and hundreds of large, highly isomorphous PSII crystals. Compared with the structure from XRD, the OEC in the X-ray free electron laser structure has Mn-Mn distances that are shorter by 0.1-0.2 ångströms. The valences of each manganese atom were tentatively assigned as Mn1D(III), Mn2C(IV), Mn3B(IV) and Mn4A(III), based on the average Mn-ligand distances and analysis of the Jahn-Teller axis on Mn(III). One of the oxo-bridged oxygens, O5, has significantly longer distances to Mn than do the other oxo-oxygen atoms, suggesting that O5 is a hydroxide ion instead of a normal oxygen dianion and therefore may serve as one of the substrate oxygen atoms. These findings provide a structural basis for the mechanism of oxygen evolution, and we expect that this structure will provide a blueprint for the design of artificial catalysts for water oxidation.
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