Evidence map›Paper›PMID 25469840›Full record

ArticleNature structural & molecular biology2014

Dynamic activation of apoptosis: conformational ensembles of cIAP1 are linked to a spring-loaded mechanism.

Michelle L Gill, R Andrew Byrd

Abstract read
In one paragraph

Article in Nature structural & molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michelle L GillStructural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.
R Andrew ByrdStructural Biophysics Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, USA.

Funding

Investigation of Protein-Protein Interactions in the ERAD Ubiquitylation PathwayZIABC011131 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BYRD, ROBERT · 2009 to 2024
$12.0M
Structural Biology of Proteins Involved in Signal Transduction and Regulation ofZ01BC010346 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BYRD, R ANDREW · 2000 to 2008
$1.7M
Intramural NIH HHS Z01 BC010346
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisAnimalsDrug DiscoveryHumansInhibitor of Apoptosis ProteinsModels, MolecularProtein ConformationProtein MultimerizationSignal TransductionUbiquitin-Protein LigasesBIRC2 protein, humanInhibitor of Apoptosis ProteinsUbiquitin-Protein Ligases

Identifiers

PMID25469840
PMCPMC6309400

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.